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[HTML][HTML] Single cell cancer epigenetics
M Casado-Pelaez, A Bueno-Costa, M Esteller - Trends in Cancer, 2022 - cell.com
Bulk sequencing methodologies have allowed us to make great progress in cancer
research. Unfortunately, these techniques lack the resolution to fully unravel the epigenetic …
research. Unfortunately, these techniques lack the resolution to fully unravel the epigenetic …
[HTML][HTML] Regulatory SNPs: altered transcription factor binding sites implicated in complex traits and diseases
AO Degtyareva, EV Antontseva… - International journal of …, 2021 - mdpi.com
The vast majority of the genetic variants (mainly SNPs) associated with various human traits
and diseases map to a noncoding part of the genome and are enriched in its regulatory …
and diseases map to a noncoding part of the genome and are enriched in its regulatory …
KAS-ATAC reveals the genome-wide single-stranded accessible chromatin landscape of the human genome
SH Kim, GK Marinov, WJ Greenleaf - Genome Research, 2025 - genome.cshlp.org
Gene regulation in most eukaryotes involves two fundamental processes: alterations in
genome packaging by nucleosomes, with active cis-regulatory elements (CREs) generally …
genome packaging by nucleosomes, with active cis-regulatory elements (CREs) generally …
Genome-wide distribution of 5-hydroxymethyluracil and chromatin accessibility in the Breviolum minutum genome
GK Marinov, X Chen, MP Swaffer, T **
GK Marinov, SH Kim, ST Bagdatli, SI Higashino… - Genome Biology, 2023 - Springer
Detecting and mitigating off-target activity is critical to the practical application of CRISPR-
mediated genome and epigenome editing. While numerous methods have been developed …
mediated genome and epigenome editing. While numerous methods have been developed …
Integrated analysis of ATAC-seq and RNA-seq reveals the transcriptional regulation network in SLE
J Wu, Y Li, D Feng, Y Yu, H Long, Z Hu, Q Lu… - International …, 2023 - Elsevier
Background CD4+ T cells have a vital role in the pathogenesis of systemic lupus
erythematosus (SLE), abnormal gene expression in CD4+ T cells partly accounting for …
erythematosus (SLE), abnormal gene expression in CD4+ T cells partly accounting for …
The chromatin landscape of the histone-possessing Bacteriovorax bacteria
Histone proteins have traditionally been thought to be restricted to eukaryotes and most
archaea, with eukaryotic nucleosomal histones deriving from their archaeal ancestors. In …
archaea, with eukaryotic nucleosomal histones deriving from their archaeal ancestors. In …
Differential regulation of male-hormones-related enhancers revealed by chromatin accessibility and transcriptional profiles in pig liver
S Chan, Y Wang, Y Luo, M Zheng, F **e, M Xue… - Biomolecules, 2024 - mdpi.com
Surgical castration can effectively avoid boar taint and improve pork quality by removing the
synthesis of androstenone in the testis, thereby reducing its deposition in adipose tissue …
synthesis of androstenone in the testis, thereby reducing its deposition in adipose tissue …
Human-genome single nucleotide polymorphisms affecting transcription factor binding and their role in pathogenesis
EV Antontseva, AO Degtyareva… - Vavilov Journal of …, 2023 - pmc.ncbi.nlm.nih.gov
Single nucleotide polymorphisms (SNPs) are the most common type of variation in the
human genome. The vast majority of SNPs identified in the human genome do not have any …
human genome. The vast majority of SNPs identified in the human genome do not have any …
The chromatin landscape of the euryarchaeon Haloferax volcanii
Abstract Background Archaea, together with Bacteria, represent the two main divisions of life
on Earth, with many of the defining characteristics of the more complex eukaryotes tracing …
on Earth, with many of the defining characteristics of the more complex eukaryotes tracing …