Reconsidering anion inhibitors in the general context of drug design studies of modulators of activity of the classical enzyme carbonic anhydrase
Inorganic anions inhibit the metalloenzyme carbonic anhydrase (CA, EC 4.2. 1.1) generally
by coordinating to the active site metal ion. Cyanate was reported as a non-coordinating CA …
by coordinating to the active site metal ion. Cyanate was reported as a non-coordinating CA …
Anti-obesity carbonic anhydrase inhibitors: challenges and opportunities
CT Supuran - Journal of Enzyme Inhibition and Medicinal …, 2022 - Taylor & Francis
The mitochondrial isoforms VA/VB of metalloenzyme carbonic anhydrase (CA, EC 4.2. 1.1)
are involved in metabolic processes, such as de novo lipogenesis and fatty acid …
are involved in metabolic processes, such as de novo lipogenesis and fatty acid …
Multi-and poly-pharmacology of carbonic anhydrase inhibitors
CT Supuran - Pharmacological Reviews, 2024 - Elsevier
Eight genetically distinct families of the enzyme carbonic anhydrase (CA, EC 4.2. 1.1) were
described in organisms allover the phylogenetic tree. They catalyze the hydration of CO 2 to …
described in organisms allover the phylogenetic tree. They catalyze the hydration of CO 2 to …
Factors affecting flavor perception in space: Does the spacecraft environment influence food intake by astronauts?
AJ Taylor, JD Beauchamp, L Briand… - … reviews in food …, 2020 - Wiley Online Library
The intention to send a crewed mission to Mars involves a huge amount of planning to
ensure a safe and successful mission. Providing adequate amounts of food for the crew is a …
ensure a safe and successful mission. Providing adequate amounts of food for the crew is a …
Sulphonamide inhibition studies of the β-carbonic anhydrase GsaCAβ present in the salmon platyhelminth parasite Gyrodactylus salaris
A β-class carbonic anhydrase (CA, EC 4.2. 1.1) present in the genome of the Monogenean
platyhelminth Gyrodactylus salaris, a fish parasite, GsaCAβ, has been investigated for its …
platyhelminth Gyrodactylus salaris, a fish parasite, GsaCAβ, has been investigated for its …
Taste and Appetite at Altitude: A Comprehensive Review of Sensory and Hunger Modulation in High-Altitude Environments
Introduction: Individuals living or working at high altitudes typically experience altered taste
perceptions and reduced appetite. These changes can lead to nutritional deficiencies …
perceptions and reduced appetite. These changes can lead to nutritional deficiencies …
Sulfonamide Inhibition Studies of a New β-Carbonic Anhydrase from the Pathogenic Protozoan Entamoeba histolytica
A newly described β-carbonic anhydrase (CA, EC 4.2. 1.1) from the pathogenic protozoan
Entamoeba histolytica, EhiCA, was recently shown to possess a significant catalytic activity …
Entamoeba histolytica, EhiCA, was recently shown to possess a significant catalytic activity …
Weight loss in idiopathic intracranial hypertension: a retrospective review of outcomes in the clinical setting
JL Ang, KZ Teo, CL Fraser - Journal of Neuro-Ophthalmology, 2021 - journals.lww.com
Background: Weight loss is important in the management of idiopathic intracranial
hypertension (IIH); however, extremely caloric restrictive diets have been used in published …
hypertension (IIH); however, extremely caloric restrictive diets have been used in published …
[HTML][HTML] Acetazolamide increases locomotion, exploratory behavior, and weight loss following social stress: A treatment for emotional eating?
R Woodman, J Student, T Malcolm, C Miller… - Metabolism Open, 2020 - Elsevier
Sympathomimetics are effective, centrally acting drugs that induce weight loss through their
potent anorexic and locomotor properties. We reported that sympathomimetics antagonize …
potent anorexic and locomotor properties. We reported that sympathomimetics antagonize …
Hybrid Pharmacophores as Carbonic Anhydrase Inhibitors
S Bua - 2020 - flore.unifi.it
Carbonic anhydrases (CAs, EC 4.2. 1.1) are ubiquitous metalloenzymes encoded in most
organisms of the tree of life and classified in eight evolutionarily unrelated families: α-, β-, γ …
organisms of the tree of life and classified in eight evolutionarily unrelated families: α-, β-, γ …