The Lord of the Lungs: The essential role of pulmonary surfactant upon inhalation of nanoparticles

C Garcia-Mouton, A Hidalgo, A Cruz… - European Journal of …, 2019 - Elsevier
The rapid development of nanotechnology is opening a huge world of promising
possibilities in healthcare, but this is also increasing the necessity to study the potential risk …

A toxicological profile of silica nanoparticles

JY Liu, CM Sayes - Toxicology Research, 2022 - academic.oup.com
Humans are regularly exposed to silica nanoparticles in environmental and occupational
contexts, and these exposures have been implicated in the onset of adverse health effects …

Interactions of particulate matter and pulmonary surfactant: Implications for human health

F Wang, J Liu, H Zeng - Advances in colloid and interface science, 2020 - Elsevier
Particulate matter (PM), which is the primary contributor to air pollution, has become a
pervasive global health threat. When PM enters into a respiratory tract, the first body tissues …

Interaction of inhalable volatile organic compounds and pulmonary surfactant: Potential hazards of VOCs exposure to lung

Q Zhao, Y Li, X Chai, L Xu, L Zhang, P Ning… - Journal of hazardous …, 2019 - Elsevier
Exposure of volatile organic compounds (VOCs) towards lung leads to pulmonary
dysfunctions and various lung diseases. However, the interaction of VOCs with pulmonary …

Physicochemical properties of nanoparticles affecting their fate and the physiological function of pulmonary surfactants

Q Liu, J Guan, R Song, X Zhang, S Mao - Acta biomaterialia, 2022 - Elsevier
Pulmonary drug delivery has drawn great attention due to its targeted local lung action,
reduced side effects, and ease of administration. However, inhaled nanoparticles (NPs) …

[HTML][HTML] Physiological fluid interfaces: Functional microenvironments, drug delivery targets, and first line of defense

P Bertsch, J Bergfreund, EJ Windhab, P Fischer - Acta Biomaterialia, 2021 - Elsevier
Fluid interfaces, ie the boundary layer of two liquids or a liquid and a gas, play a vital role in
physiological processes as diverse as visual perception, oral health and taste, lipid …

Lung surfactant-particles at fluid interfaces for toxicity assessments

E Guzmán, E Santini - Current Opinion in Colloid & Interface Science, 2019 - Elsevier
Lung surfactant is a complex mixture of lipids and proteins which plays a major role in the
respiratory cycle. This makes necessary to understand the effects of different external factors …

Physicochemical studies of direct interactions between lung surfactant and components of electronic cigarettes liquid mixtures

TR Sosnowski, K Jabłczyńska, M Odziomek… - Inhalation …, 2018 - Taylor & Francis
Direct physicochemical interactions between the major components of electronic cigarette
liquids (e-liquids): glycerol (VG) and propylene glycol (PG), and lung surfactant (LS) were …

Interaction of nano carbon particles and anthracene with pulmonary surfactant: The potential hazards of inhaled nanoparticles

Q Zhao, Y Li, X Chai, L Zhang, L Xu, J Huang, P Ning… - Chemosphere, 2019 - Elsevier
Understanding the alteration of the air-liquid interfacial properties of pulmonary surfactant
(PS) in the presence of nanoparticles (NPs) and polycyclic aromatic hydrocarbons (PAHs) is …

Particles on the lung surface-physicochemical and hydrodynamic effects

TR Sosnowski - Current opinion in colloid & interface science, 2018 - Elsevier
The paper highlights and discusses the role of interfacial phenomena in the interactions
between inhaled solid particles with different properties (size, structure, surface …