A large body of evidence generated in the last two and a half years addresses the roles of T
cells in SARS-CoV-2 infection and following vaccination. Infection or vaccination induces …

Immunological memory is the basis of protective immunity provided by vaccines and
previous infections. Immunological memory can develop from multiple branches of the …

In vitro-transcribed (IVT) mRNAs are modalities that can combat human disease, exemplified
by their use as vaccines for severe acute respiratory syndrome coronavirus 2 (SARS-CoV …

Background The duration and effectiveness of immunity from infection with and vaccination
against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) are relevant to …

Breakthrough infections with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-
2) in fully vaccinated individuals are receiving intense scrutiny because of their importance …

The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Omicron variant of
concern comprises several sublineages, with BA. 2 and BA. 2.12. 1 having replaced the …

Background Given the importance of flexible use of different COVID-19 vaccines within the
same schedule to facilitate rapid deployment, we studied mixed priming schedules …

Following severe adverse reactions to the AstraZeneca ChAdOx1-S-nCoV-19 vaccine,,
European health authorities recommended that patients under the age of 55 years who …

Background Since it was first identified in early November 2021, the B. 1.1. 529 (omicron)
variant of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has spread …

Immune memory is tailored by cues that lymphocytes perceive during priming. The severe
acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic created a situation in …