BPC 157 and standard angiogenic growth factors. Gastrointestinal tract healing, lessons from tendon, ligament, muscle and bone healing

S Seiwerth, R Rucman, B Turkovic… - Current …, 2018 - benthamdirect.com
Commonly, the angiogenic growth factors signify healing. However, gastrointestinal
ulceration is still poorly understood particularly with respect to a general pharmacological …

Stable gastric pentadecapeptide BPC 157 may recover brain–gut axis and gut–brain axis function

P Sikiric, S Gojkovic, I Krezic, IM Smoday, L Kalogjera… - Pharmaceuticals, 2023 - mdpi.com
Conceptually, a wide beneficial effect, both peripherally and centrally, might have been
essential for the harmony of brain–gut and gut–brain axes' function. Seen from the original …

Modulatory effects of BPC 157 on vasomotor tone and the activation of Src-Caveolin-1-endothelial nitric oxide synthase pathway

MJ Hsieh, CH Lee, HY Chueh, GJ Chang, HY Huang… - Scientific Reports, 2020 - nature.com
BPC 157-activated endothelial nitric oxide synthase (eNOS) is associated with tissue repair
and angiogenesis as reported in previous studies. However, how BPC 157 regulates the …

The effect of pentadecapeptide BPC 157 on hippocampal ischemia/reperfusion injuries in rats

J Vukojević, B Vrdoljak, D Malekinušić… - Brain and …, 2020 - Wiley Online Library
Background and purpose We focused on the, yet undescribed, therapy effect of the stable
gastric pentadecapeptide BPC 157 in hippocampal ischemia/reperfusion injuries, after …

Pentadecapeptide BPC 157 and the central nervous system

J Vukojević, M Milavić, D Perović, S Ilić… - Neural Regeneration …, 2022 - journals.lww.com
We reviewed the pleiotropic beneficial effects of the stable gastric pentadecapeptide BPC
157, three very recent demonstrations that may be essential in the gut-brain and brain-gut …

Novel cytoprotective mediator, stable gastric pentadecapeptide BPC 157. Vascular recruitment and gastrointestinal tract healing

P Sikiric, R Rucman, B Turkovic, M Sever… - Current …, 2018 - benthamdirect.com
Years ago, we revealed a novel cytoprotective mediator, stable gastric pentadecapeptide
BPC 157, particular anti-ulcer peptide that heals different organs lesions when given as a …

Stable gastric pentadecapeptide BPC 157, Robert's stomach cytoprotection/adaptive cytoprotection/organoprotection, and Selye's stress co** response: Progress …

P Sikiric, KB Hahm, AB Blagaic, A Tvrdeic… - Gut and …, 2019 - pmc.ncbi.nlm.nih.gov
We reviewed again the significance of the stable gastric pentadecapeptide BPC 157 as a
likely mediator of Robert's stomach cytoprotection/adaptive cytoprotection and …

[HTML][HTML] Pentadecapeptide BPC 157 resolves Pringle maneuver in rats, both ischemia and reperfusion

M Kolovrat, S Gojkovic, I Krezic… - World journal of …, 2020 - pmc.ncbi.nlm.nih.gov
BACKGROUND The Pringle maneuver [portal triad obstruction (PTO)] provides huge
disturbances during ischemia and even more thereafter in reperfusion. Contrarily, a possible …

[HTML][HTML] Stable gastric pentadecapeptide BPC 157 and wound healing

S Seiwerth, M Milavic, J Vukojevic, S Gojkovic… - Frontiers in …, 2021 - frontiersin.org
Significance: The antiulcer peptide, stable gastric pentadecapeptide BPC 157 (previously
employed in ulcerative colitis and multiple sclerosis trials, no reported toxicity (LD1 not …