[HTML][HTML] Hepatitis B virus molecular biology and pathogenesis

RJ Lamontagne, S Bagga, MJ Bouchard - Hepatoma research, 2016 - ncbi.nlm.nih.gov
As obligate intracellular parasites, viruses need a host cell to provide a milieu favorable to
viral replication. Consequently, viruses often adopt mechanisms to subvert host cellular …

Systematic review: chronic viral hepatitis and metabolic derangement

CC Wang, PN Cheng, JH Kao - Alimentary pharmacology & …, 2020 - Wiley Online Library
Background The liver has a critical role in the metabolism of glucose and lipids. Chronic
hepatitis B virus (HBV) or hepatitis C virus (HCV) infection leads to a spectrum of liver …

[HTML][HTML] PCSK9 and cancer: Rethinking the link

K Mahboobnia, M Pirro, E Marini, F Grignani… - Biomedicine & …, 2021 - Elsevier
Background Cancer is emerging as a major problem globally, as it accounts for the second
cause of death despite medical advances. According to epidemiological and basic studies …

[HTML][HTML] Apolipoprotein Ea multifunctional protein with implications in various pathologies as a result of its structural features

IF Tudorache, VG Trusca, AV Gafencu - Computational and structural …, 2017 - Elsevier
Abstract Apolipoprotein E (apoE), a 34 kDa glycoprotein, mediates hepatic and extrahepatic
uptake of plasma lipoproteins and cholesterol efflux from lipid-laden macrophages. In …

[HTML][HTML] Gut microbiota and host metabolism in liver cirrhosis

M Usami, M Miyoshi, H Yamashita - World journal of …, 2015 - ncbi.nlm.nih.gov
The gut microbiota has the capacity to produce a diverse range of compounds that play a
major role in regulating the activity of distal organs and the liver is strategically positioned …

[HTML][HTML] Metabolic programming of macrophage functions and pathogens control

S Koo, NJ Garg - Redox biology, 2019 - Elsevier
Macrophages (Mφ) are central players in mediating proinflammatory and
immunomodulatory functions. Unchecked Mφ activities contribute to pathology across many …

Recent advances in glycyrrhizin metabolism, health benefits, clinical effects and drug delivery systems for efficacy improvement; a comprehensive review

AF Bakr, P Shao, MA Farag - Phytomedicine, 2022 - Elsevier
Background Glycyrrhizin (GL) is a major active constituent of licorice root (Glycyrrhiza
glabra) that is considered one of the oldest and most frequently employed botanicals in …

Association between cardiometabolic risk factors and COVID-19 susceptibility, severity and mortality: a review

Y Sharifi, M Payab, E Mohammadi-Vajari… - Journal of Diabetes & …, 2021 - Springer
The novel coronavirus, which began spreading from China Wuhan and gradually spreaded
to most countries, led to the announcement by the World Health Organization on March 11 …

[HTML][HTML] Chronic hepatitis C virus infection and lipoprotein metabolism

Y Aizawa, N Seki, T Nagano, H Abe - World Journal of …, 2015 - ncbi.nlm.nih.gov
Hepatitis C virus (HCV) is a hepatotrophic virus and a major cause of chronic liver disease,
including hepatocellular carcinoma, worldwide. The life cycle of HCV is closely associated …

[HTML][HTML] Hepatitis C virus relies on lipoproteins for its life cycle

G Grassi, G Di Caprio, GM Fimia, G Ippolito… - World journal of …, 2016 - ncbi.nlm.nih.gov
Hepatitis C virus (HCV) infects over 150 million people worldwide. In most cases, HCV
infection becomes chronic causing liver disease ranging from fibrosis to cirrhosis and …