What are the key gut microbiota involved in neurological diseases? A systematic review
There is a growing body of evidence highlighting there are significant changes in the gut
microbiota composition and relative abundance in various neurological disorders. We …
microbiota composition and relative abundance in various neurological disorders. We …
The pathological effects of circulating hydrophobic bile acids in Alzheimer's disease
T Ehtezazi, K Rahman, R Davies… - Journal of Alzheimer's …, 2023 - content.iospress.com
Recent clinical studies have revealed that the serum levels of toxic hydrophobic bile acids
(deoxy cholic acid, lithocholic acid [LCA], and glycoursodeoxycholic acid) are significantly …
(deoxy cholic acid, lithocholic acid [LCA], and glycoursodeoxycholic acid) are significantly …
Aberrant bowel movement frequencies coincide with increased microbe-derived blood metabolites associated with reduced organ function
Bowel movement frequency (BMF) directly impacts the gut microbiota and is linked to
diseases like chronic kidney disease or dementia. In particular, prior work has shown that …
diseases like chronic kidney disease or dementia. In particular, prior work has shown that …
Berberine improves behavioral and cognitive deficits in a mouse model of alzheimer's disease via regulation of β-amyloid production and endoplasmic reticulum …
Y Liang, C Ye, Y Chen, Y Chen, S Diao… - ACS Chemical …, 2021 - ACS Publications
Alzheimer's disease (AD) is a neurodegenerative disease characterized by β-amyloid (Aβ),
neurofibrillary tangles, and neuronal cell death. Aggressive Aβ accumulation accelerates …
neurofibrillary tangles, and neuronal cell death. Aggressive Aβ accumulation accelerates …
GSH-AuNP anti-oxidative stress, ER stress and mitochondrial dysfunction in amyloid-beta peptide-treated human neural stem cells
MC Chiang, CJB Nicol - Free Radical Biology and Medicine, 2022 - Elsevier
Amyloid-beta (Aβ) peptides have a role in the pathogenesis of Alzheimer's disease (AD) and
are thought to promote oxidative stress, endoplasmic reticulum (ER) stress and …
are thought to promote oxidative stress, endoplasmic reticulum (ER) stress and …
[HTML][HTML] Slow gut transit increases the risk of Alzheimer's disease: an integrated study of the bi-national cohort in South Korea and Japan and Alzheimer's disease …
Introduction Although the association between Alzheimer's disease (AD) and constipation is
controversial, its causality and underlying mechanisms remain unknown. Objectives To …
controversial, its causality and underlying mechanisms remain unknown. Objectives To …
Investigating gut alterations in Alzheimer's disease: In-depth analysis with micro-and nano-3D X-ray phase contrast tomography
Alzheimer's disease (AD), a debilitating neurodegenerative disorder, remains one of the
foremost public health challenges affecting more than 30 million people worldwide with the …
foremost public health challenges affecting more than 30 million people worldwide with the …
Dysbiosis of fecal microbiota from complement 3 knockout mice with constipation phenotypes contributes to development of defecation delay
YJ Choi, JE Kim, SJ Lee, JE Gong, HJ Son… - Frontiers in …, 2021 - frontiersin.org
Significant phenotypes for constipation were detected in complement 3 (C3) knockout (KO)
mice, although no research has been conducted on an association with alteration of gut …
mice, although no research has been conducted on an association with alteration of gut …
Similarities and differences in constipation phenotypes between Lep knockout mice and high fat diet-induced obesity mice
JE Kim, A Seol, YJ Choi, SJ Lee, YJ **, YJ Roh… - PLoS …, 2022 - journals.plos.org
CRISPR-Cas9-mediated leptin (Lep) knockout (KO) mice exhibited prominent phenotypes
for constipation, even though they were not compared with other model animals. This study …
for constipation, even though they were not compared with other model animals. This study …
Cholinergic Receptor Muscarinic 1 co-localized with mitochondria in cultured dorsal root ganglion neurons, and its deletion disrupted mitochondrial ultrastructure in …
MG Sabbir - Journal of Alzheimer's Disease, 2024 - content.iospress.com
Background: Loss of Cholinergic Receptor Muscarinic 1 (CHRM1) has been linked to the
pathogenesis of Alzheimer's disease (AD). Our recent study found significantly lower …
pathogenesis of Alzheimer's disease (AD). Our recent study found significantly lower …