[HTML][HTML] Advances in the development of amorphous solid dispersions: The role of polymeric carriers

J Zhang, M Guo, M Luo, T Cai - Asian Journal of Pharmaceutical Sciences, 2023 - Elsevier
Amorphous solid dispersion (ASD) is one of the most effective approaches for delivering
poorly soluble drugs. In ASDs, polymeric materials serve as the carriers in which the drugs …

Recent advances in drug polymorphs: Aspects of pharmaceutical properties and selective crystallization

Q Shi, H Chen, Y Wang, J Xu, Z Liu, C Zhang - International journal of …, 2022 - Elsevier
Drug polymorphism, an established term used to describe the phenomenon that a drug can
exist in different crystalline phases, has attracted great interests in pharmaceutical field in …

A review on thermophysical properties and thermal stability of sugar alcohols as phase change materials

S Tomassetti, A Aquilanti, PF Muciaccia… - Journal of Energy …, 2022 - Elsevier
The increasing use of renewable energy sources has highlighted the importance of energy
storages, and in particular of latent heat thermal energy storages (LHTESs). Among the …

[HTML][HTML] Amorphous solid dispersions: role of the polymer and its importance in physical stability and in vitro performance

Q Shi, H Chen, Y Wang, R Wang, J Xu, C Zhang - Pharmaceutics, 2022 - mdpi.com
Amorphous solid dispersions stabilized by one or more polymer (s) have been widely used
for delivering amorphous drugs with poor water solubilities, and they have gained great …

Anisotropic molecular organization at a liquid/vapor interface promotes crystal nucleation with polymorph selection

X Yao, Q Liu, B Wang, J Yu, MM Aristov… - Journal of the …, 2022 - ACS Publications
The molecules at the surface of a liquid have different organization and dynamics from those
in the bulk, potentially altering the rate of crystal nucleation and polymorphic selection, but …

Recent advances in polymorph discovery methods of organic crystals

C Yao, S Zhang, L Wang, X Tao - Crystal Growth & Design, 2022 - ACS Publications
Polymorphism, the ability of the same substance to crystallize in more than one crystal
structure, is a common phenomenon in organic crystals, influencing the physicochemical …

Ritonavir Form III: A new polymorph after 24 years

X Yao, RF Henry, GGZ Zhang - Journal of pharmaceutical sciences, 2023 - Elsevier
Polymorphism occurs widely in pharmaceutical solids, and must be thoroughly studied
during product development. Twenty-four years after ritonavir (RTV) Form II materialized, we …

Recent crucial discoveries and perspectives on crystal nucleation in supercooled liquids and oxide glasses

LR Rodrigues, MHR Acosta, ED Zanotto - Progress in Materials Science, 2023 - Elsevier
Due to their measurable crystallization kinetics, oxide glass-formers are adequate systems
for evaluating theoretical approaches to describe and predict crystal nucleation dynamics …

[HTML][HTML] Polymorphic selectivity in crystal nucleation

Y Gui, C Huang, C Shi, T Stelzer… - The Journal of chemical …, 2022 - pubs.aip.org
Crystal nucleation rates have been measured in the supercooled melts of two richly
polymorphic glass-forming liquids: ROY and nifedipine (NIF). ROY or 5-methyl-2-[(2 …

The twelfth solved structure of ROY: single crystals of Y04 grown from melt microdroplets

X Li, X Ou, H Rong, S Huang, J Nyman… - Crystal Growth & …, 2020 - ACS Publications
Form Y04 of the compound ROY is a transient polymorph discovered by melt crystallization
in 2004, whose structure has not yet been determined. Here we report the structure of Form …