Perspective on the current state-of-the-art of quantum computing for drug discovery applications

NS Blunt, J Camps, O Crawford, R Izsák… - Journal of Chemical …, 2022‏ - ACS Publications
Computational chemistry is an essential tool in the pharmaceutical industry. Quantum
computing is a fast evolving technology that promises to completely shift the computational …

Combining machine learning and computational chemistry for predictive insights into chemical systems

JA Keith, V Vassilev-Galindo, B Cheng… - Chemical …, 2021‏ - ACS Publications
Machine learning models are poised to make a transformative impact on chemical sciences
by dramatically accelerating computational algorithms and amplifying insights available from …

100 years of the Lennard-Jones potential

P Schwerdtfeger, DJ Wales - Journal of Chemical Theory and …, 2024‏ - ACS Publications
It is now 100 years since Lennard-Jones published his first paper introducing the now
famous potential that bears his name. It is therefore timely to reflect on the many …

Coarse-grained modelling out of equilibrium

T Schilling - Physics Reports, 2022‏ - Elsevier
Abstract Active matter, responsive (“smart”) materials and materials under time-dependent
load are systems out of thermal equilibrium. To construct coarse-grained models for such …

Multiscale modelling of photoinduced processes in composite systems

B Mennucci, S Corni - Nature Reviews Chemistry, 2019‏ - nature.com
In the past few decades, quantum mechanical (QM) modelling has moved from isolated
molecules made of few atoms to large supramolecular aggregates embedded in complex …

QUBEKit: Automating the derivation of force field parameters from quantum mechanics

JT Horton, AEA Allen, LS Dodda… - Journal of chemical …, 2019‏ - ACS Publications
Modern molecular mechanics force fields are widely used for modeling the dynamics and
interactions of small organic molecules using libraries of transferable force field parameters …

Adsorption of the most common non-steroidal analgesics from aquatic environment on agricultural wastes-based activated carbons; experimental adsorption study …

L Matějová, J Bednárek, J Tokarský, I Koutník… - Applied Surface …, 2022‏ - Elsevier
Adsorption experiments and force-field based molecular modeling of analgesics interactions
with carbon structures were applied to study the adsorption of diclofenac sodium salt …

Ab Initio Prediction of Vapor Pressure for Diverse Atomic Layer Deposition Precursors

A Odinokov, WJ Son, A Yakubovich… - Journal of Chemical …, 2024‏ - ACS Publications
Understanding the saturated vapor pressure (P vap) is vital for evaluating atomic layer
deposition (ALD) precursors, as it directly influences the ALD temperature window and, by …

Paramol: A package for automatic parameterization of molecular mechanics force fields

J Morado, PN Mortenson, ML Verdonk… - Journal of Chemical …, 2021‏ - ACS Publications
The ensemble of structures generated by molecular mechanics (MM) simulations is
determined by the functional form of the force field employed and its parameterization. For a …

The effective fragment molecular orbital method: Achieving high scalability and accuracy for large systems

T Sattasathuchana, P Xu, C Bertoni… - Journal of Chemical …, 2024‏ - ACS Publications
The effective fragment molecular orbital (EFMO) method has been developed to predict the
total energy of a very large molecular system accurately (with respect to the underlying …