Learning is an essential biological process for survival since it facilitates behavioural
plasticity in response to environmental changes. This process is mediated by a wide variety …

A hallmark of adaptive behavior is the ability to flexibly respond to sensory cues. To
understand how neural circuits implement this flexibility, it is critical to resolve how a static …

Animals must weigh competing needs and states to generate adaptive behavioral
responses to the environment. Sensorimotor circuits are thus tasked with integrating diverse …

Maintaining or shifting between behavioral states according to context is essential for
animals to implement fitness-promoting strategies. How the integration of internal state, past …

Neurons modify their transcriptomes in response to an animal's experience. How specific
experiences are transduced to modulate gene expression and precisely tune neuronal …

Studies of neuronal connectivity in model organisms, ie, of their connectomes, have been
instrumental in dissecting the structure-function relationship of nervous systems. However …

Internal state profoundly alters perception and behavior. For example, a starved fly may
approach and consume foods that it would otherwise find undesirable. A socially engaged …

An animal's ability to sense odors declines during aging, and its olfactory drive is tuned by
internal states such as satiety. However, whether internal states modulate an age …

Survival in animals relies on navigating environments aligned with physiological needs. In
Drosophila melanogaster, antennal ionotropic receptors (IRs) sensing humidity changes …

Neurexins are synaptic adhesion molecules that play diverse roles in synaptic development,
function, maintenance, and plasticity. Neurexin genes have been associated with changes …