Computer-aided design techniques for flow-based microfluidic lab-on-a-chip systems

X Huang, TY Ho, W Guo, B Li, K Chakrabarty… - ACM Computing …, 2021 - dl.acm.org
As one of the most promising lab-on-a-chip systems, flow-based microfluidic biochips are
being increasingly used for automatically executing various laboratory procedures in biology …

Overcoming technological barriers in microfluidics: Leakage testing

V Silverio, S Guha, A Keiser, R Natu… - … in bioengineering and …, 2022 - frontiersin.org
The miniaturization of laboratory procedures for Lab-on-Chip (LoC) devices and translation
to various platforms such as single cell analysis or Organ-on-Chip (OoC) systems are …

Design automation for continuous-flow microfluidic biochips: A comprehensive review

G Liu, H Huang, Z Chen, H Lin, H Liu, X Huang, W Guo - Integration, 2022 - Elsevier
Continuous-flow microfluidic biochips (CFMBs), also known as lab-on-a-chip platforms, have
attracted considerable attentions in the past two decades and have been widely used in …

Flow-based microfluidic biochips with distributed channel storage: Synthesis, physical design, and wash optimization

X Huang, W Guo, Z Chen, B Li, TY Ho… - IEEE Transactions …, 2021 - ieeexplore.ieee.org
System-architecture design optimization of flow-based microfluidic biochips has been
extensively investigated over the past decade. Most of the prior work, however, is still based …

Control-layer routing and control-pin minimization for flow-based microfluidic biochips

K Hu, TA Dinh, TY Ho… - IEEE Transactions on …, 2016 - ieeexplore.ieee.org
Recent advances in flow-based microfluidic biochips have enabled the emergence of lab-on-
a-chip devices for bimolecular recognition and point-of-care disease diagnostics. However …

Computer-aided design of microfluidic circuits

EE Tsur - Annual review of biomedical engineering, 2020 - annualreviews.org
Microfluidic devices developed over the past decade feature greater intricacy, increased
performance requirements, new materials, and innovative fabrication methods …

3DμF - Interactive Design Environment for Continuous Flow Microfluidic Devices

R Sanka, J Lippai, D Samarasekera, S Nemsick… - Scientific reports, 2019 - nature.com
The design of microfluidic Lab on a Chip (LoC) systems is an onerous task requiring
specialized skills in fluid dynamics, mechanical design drafting, and manufacturing …

Testing microfluidic fully programmable valve arrays (FPVAs)

C Liu, B Li, BB Bhattacharya… - … , Automation & Test …, 2017 - ieeexplore.ieee.org
Fully Programmable Valve Array (FPVA) has emerged as a new architecture for the next-
generation flow-based microfluidic biochips. This 2D-array consists of regularly-arranged …

Timing-driven flow-channel network construction for continuous-flow microfluidic biochips

X Huang, TY Ho, K Chakrabarty… - IEEE Transactions on …, 2019 - ieeexplore.ieee.org
The emergence of flow-based microfluidic biochips (FBMBs) has increased the automation
level of biochemical procedures, and these lab-on-a-chip devices are now being used for …

Transport or store? Synthesizing flow-based microfluidic biochips using distributed channel storage

C Liu, B Li, H Yao, P Pop, TY Ho… - Proceedings of the 54th …, 2017 - dl.acm.org
Flow-based microfluidic biochips have attracted much attention in the EDA community due
to their miniaturized size and execution efficiency. Previous research, however, still follows …