Bond-forming and-breaking reactions at sulfur (IV): sulfoxides, sulfonium salts, sulfur ylides, and sulfinate salts

D Kaiser, I Klose, R Oost, J Neuhaus… - Chemical …, 2019 - ACS Publications
Organosulfur compounds have long played a vital role in organic chemistry and in the
development of novel chemical structures and architectures. Prominent among these …

18F-Labeling of Arenes and Heteroarenes for Applications in Positron Emission Tomography

S Preshlock, M Tredwell, V Gouverneur - Chemical reviews, 2016 - ACS Publications
Diverse radiochemistry is an essential component of nuclear medicine; this includes
imaging techniques such as positron emission tomography (PET). As such, PET can track …

Chemistry for Positron Emission Tomography: Recent Advances in 11C‐, 18F‐, 13N‐, and 15O‐Labeling Reactions

X Deng, J Rong, L Wang, N Vasdev… - Angewandte Chemie …, 2019 - Wiley Online Library
Positron emission tomography (PET) is a molecular imaging technology that provides
quantitative information about function and metabolism in biological processes in vivo for …

Concerted nucleophilic aromatic substitution with 19F and 18F

CN Neumann, JM Hooker, T Ritter - Nature, 2016 - nature.com
Nucleophilic aromatic substitution (SNAr) is widely used by organic chemists to functionalize
aromatic molecules, and it is the most commonly used method to generate arenes that …

Fluorine-18 labelled building blocks for PET tracer synthesis

D Van Der Born, A Pees, AJ Poot, RVA Orru… - Chemical Society …, 2017 - pubs.rsc.org
Positron emission tomography (PET) is an important driver for present day healthcare.
Fluorine-18 is the most widely used radioisotope for PET imaging and a thorough overview …

Synthesis of [18F]Arenes via the Copper-Mediated [18F]Fluorination of Boronic Acids

AV Mossine, AF Brooks, KJ Makaravage, JM Miller… - Organic …, 2015 - ACS Publications
A copper-mediated radiofluorination of aryl-and vinylboronic acids with K18F is described.
This method exhibits high functional group tolerance and is effective for the radiofluorination …

A leap forward in sulfonium salt and sulfur ylide chemistry

R Fan, C Tan, Y Liu, Y Wei, X Zhao, X Liu, J Tan… - Chinese Chemical …, 2021 - Elsevier
Sulfonium salts and sulfur ylides are important S (IV) motifs, and have displayed many
unique reactivities to provide simple, effective, and often stereoselective synthesis toward …

Copper-Mediated Radiofluorination of Arylstannanes with [18F]KF

KJ Makaravage, AF Brooks, AV Mossine… - Organic …, 2016 - ACS Publications
A copper-mediated nucleophilic radiofluorination of aryl-and vinylstannanes with [18F] KF is
described. This method is fast, uses commercially available reagents, and is compatible with …

Spirocyclic hypervalent iodine (III)-mediated radiofluorination of non-activated and hindered aromatics

BH Rotstein, NA Stephenson, N Vasdev… - Nature …, 2014 - nature.com
Abstract Fluorine-18 (t ½= 109.7 min) is the most commonly used isotope to prepare
radiopharmaceuticals for molecular imaging by positron emission tomography (PET) …

Radiosyntheses using fluorine-18: the art and science of late stage fluorination

EL Cole, MN Stewart, R Littich… - Current topics in …, 2014 - ingentaconnect.com
Positron (β+) emission tomography (PET) is a powerful, noninvasive tool for the in vivo, three-
dimensional imaging of physiological structures and biochemical pathways. The continued …