Supramolecular DNA recognition
MJ Hannon - Chemical Society Reviews, 2007 - pubs.rsc.org
Non-covalent DNA-recognition by synthetic agents is surveyed in this tutorial review, and
contrasted with biomolecular DNA-recognition. The principles and forces involved in DNA …
contrasted with biomolecular DNA-recognition. The principles and forces involved in DNA …
Interactions of small molecules with DNA junctions
The four natural DNA bases (A, T, G and C) associate in base pairs (A= T and G≡ C),
allowing the attached DNA strands to assemble into the canonical double helix of DNA (or …
allowing the attached DNA strands to assemble into the canonical double helix of DNA (or …
[BOOK][B] Nucleic acids in chemistry and biology
GM Blackburn - 2006 - books.google.com
The structure, function and reactions of nucleic acids are central to molecular biology and
are crucial for the understanding of complex biological processes involved. Revised and …
are crucial for the understanding of complex biological processes involved. Revised and …
[HTML][HTML] Major achievements in the design of quadruplex-interactive small molecules
Organic small molecules that can recognize and bind to G-quadruplex and i-Motif nucleic
acids have great potential as selective drugs or as tools in drug target discovery programs …
acids have great potential as selective drugs or as tools in drug target discovery programs …
Targeting DNA junction sites by bis-intercalators induces topological changes with potent antitumor effects
SC Huang, CW Chen, R Satange… - Nucleic Acids …, 2024 - academic.oup.com
Targeting inter-duplex junctions in catenated DNA with bidirectional bis-intercalators is a
potential strategy for enhancing anticancer effects. In this study, we used d (CGTATACG) 2 …
potential strategy for enhancing anticancer effects. In this study, we used d (CGTATACG) 2 …
Non-G base tetrads
Tetrads (or quartets) are arrangements of four nucleobases commonly involved in the
stability of four-stranded nucleic acids structures. Four-stranded or quadruplex structures …
stability of four-stranded nucleic acids structures. Four-stranded or quadruplex structures …
DNA and the chromosome–varied targets for chemotherapy
The nucleus of the cell serves to maintain, regulate, and replicate the critical genetic
information encoded by the genome. Genomic DNA is highly associated with proteins that …
information encoded by the genome. Genomic DNA is highly associated with proteins that …
Ligand Bridging of the DNA Holliday Junction: Molecular Recognition of a Stacked‐X Four‐Way Junction by a Small Molecule
AL Brogden, NH Hopcroft, M Searcey… - Angewandte Chemie …, 2007 - Wiley Online Library
Homologous recombination (HR) in the repair of a collapsed replication fork is a process
that involves strand invasion, branch migration, and resolution of the resulting Holliday …
that involves strand invasion, branch migration, and resolution of the resulting Holliday …
Assessing the differential affinity of small molecules for noncanonical DNA structures
The targeting of higher‐order DNA structures has been thoroughly developed with G‐
quadruplex DNA but not with other structures like branched DNA (also known as DNA …
quadruplex DNA but not with other structures like branched DNA (also known as DNA …
Thread Insertion of a Bis (dipyridophenazine) Diruthenium Complex into the DNA Double Helix by the Extrusion of AT Base Pairs and Cross‐Linking of DNA Duplexes
The crystal structure of the Δ, Δ enantiomer of the binuclear “light‐switch” ruthenium complex
[μ‐(11, 11′‐bidppz)(1, 10‐phenanthroline) 4 Ru2] 4+ bound to the oligonucleotide d …
[μ‐(11, 11′‐bidppz)(1, 10‐phenanthroline) 4 Ru2] 4+ bound to the oligonucleotide d …