DNA replication timing
Patterns of replication within eukaryotic genomes correlate with gene expression, chromatin
structure, and genome evolution. Recent advances in genome-scale map** of replication …
structure, and genome evolution. Recent advances in genome-scale map** of replication …
Stochastic mechano-chemical kinetics of molecular motors: a multidisciplinary enterprise from a physicist's perspective
D Chowdhury - Physics Reports, 2013 - Elsevier
A molecular motor is made of either a single macromolecule or a macromolecular complex.
Just like their macroscopic counterparts, molecular motors “transduce” input energy into …
Just like their macroscopic counterparts, molecular motors “transduce” input energy into …
Genome-wide map** of human DNA replication by optical replication map** supports a stochastic model of eukaryotic replication
The heterogeneous nature of eukaryotic replication kinetics and the low efficiency of
individual initiation sites make map** the location and timing of replication initiation in …
individual initiation sites make map** the location and timing of replication initiation in …
Modeling genome‐wide replication kinetics reveals a mechanism for regulation of replication timing
Microarrays are powerful tools to probe genome‐wide replication kinetics. The rich data sets
that result contain more information than has been extracted by current methods of analysis …
that result contain more information than has been extracted by current methods of analysis …
A chromatin structure‐based model accurately predicts DNA replication timing in human cells
The metazoan genome is replicated in precise cell lineage‐specific temporal order.
However, the mechanism controlling this orchestrated process is poorly understood as no …
However, the mechanism controlling this orchestrated process is poorly understood as no …
Replication timing and its emergence from stochastic processes
The temporal organization of DNA replication has puzzled cell biologists since before the
mechanism of replication was understood. The realization that replication timing correlates …
mechanism of replication was understood. The realization that replication timing correlates …
Mathematical modelling of whole chromosome replication
All chromosomes must be completely replicated prior to cell division, a requirement that
demands the activation of a sufficient number of appropriately distributed DNA replication …
demands the activation of a sufficient number of appropriately distributed DNA replication …
[KİTAP][B] Embryogenesis explained
The greatest mystery of life is how a single fertilized egg develops into a fully functioning,
sometimes conscious multicellular organism. Embryogenesis Explained offers a new theory …
sometimes conscious multicellular organism. Embryogenesis Explained offers a new theory …
DNA replication timing: Biochemical mechanisms and biological significance
N Rhind - BioEssays, 2022 - Wiley Online Library
The regulation of DNA replication is a fascinating biological problem both from a
mechanistic angle—How is replication timing regulated?—and from an evolutionary one …
mechanistic angle—How is replication timing regulated?—and from an evolutionary one …
Reconciling stochastic origin firing with defined replication timing
Eukaryotic chromosomes replicate with defined timing patterns. However, the mechanism
that regulates the timing of replication is unknown. In particular, there is an apparent conflict …
that regulates the timing of replication is unknown. In particular, there is an apparent conflict …