Background Fungal infections of the central nervous system (FIs-CNS) have become
significantly more common over the past 2 decades. Invasion of the CNS largely depends on …

Histoplasmosis in Africa has markedly increased since the advent of the HIV/AIDS epidemic
but is under-recognised. Pulmonary histoplasmosis may be misdiagnosed as tuberculosis …

Fungal infections of the CNS are challenging to treat and their optimal management requires
knowledge of their epidemiology, host characteristics, diagnostic criteria, and therapeutic …

Central nervous system (CNS) involvement occurs in 5 to 10% of individuals with
disseminated histoplasmosis. Most experience has been derived from small single center …

Skull base osteomyelitis (SBO) is a complex and fatal clinical entity that is often
misdiagnosed for malignancy. SBO is commonly a direct complication of otogenic …

Histoplasma capsulatum, the etiologic agent of histoplasmosis, is a dimorphic fungus highly
endemic to the Mississippi and Ohio River valleys of North America. In an increasingly …

Purpose. Previous epidemiological and cost studies of fungal meningitis have largely
focused on single pathogens, leading to a poor understanding of the disease in general. We …

Alzheimer's Disease (AD) is a neurodegenerative disorder that leads to progressive
cognitive decline, severely impacting memory, cognition, and behavior. It is the most …

Background The knowledge of central nervous system (CNS) histoplasmosis is limited to
case reports and series. Objectives Our objective was to synthesise clinical, radiological and …

Although uncommon in children, fungal infections of the central nervous system can be
devastating and difficult to treat. A better understanding of basic mycologic, immunologic …