Antibiotic therapy through short-term or repeated long-term prescriptions can have several
damaging effects on the normal microbiota of the gastrointestinal tract. Changes in …

Asthma is a common chronic respiratory disease affecting more than 300 million people
worldwide. Clinical features of asthma and its immunological and molecular etiology vary …

This document provides clinical recommendations for the management of severe asthma.
Comprehensive evidence syntheses, including meta-analyses, were performed to …

Worldwide 300 million children and adults are affected by asthma. The development of
asthma is influenced by environmental and other exogenous factors synergizing with …

Healthy human lungs have traditionally been considered to be a sterile organ. However,
culture-independent molecular techniques have reported that large numbers of microbes …

Antimicrobial resistance (AMR) poses a worldwide threat to human health and biosecurity.
The spread of antibiotic resistance genes (ARGs) via conjugative plasmid transfer is a major …

Background Chronic airway inflammation is the main driver of pathogenesis in respiratory
diseases such as severe asthma, chronic obstructive pulmonary disease, cystic fibrosis (CF) …

Non‐T2 asthma is traditionally defined as asthma without features of T2 asthma. The
definition is arbitrary and is generally based on the presence of neutrophils in sputum, or the …

Azithromycin (AZM) is a synthetic macrolide antibiotic effective against a broad range of
bacterial and mycobacterial infections. Due to an additional range of anti‐viral and anti …

Asthma is a heterogenous chronic inflammatory lung disease with endotypes that manifest
different immune system profiles, severity, and responses to current therapies. Regardless of …