Almost 50% of the infertility cases are due to male factors. Assisted reproductive
technologies (ARTs) allow to overcome the incapacity of these patients' spermatozoa to …

Considering the complexity of the current framework in oncology, the relevance of animal
models in biomedical research is critical in light of the capacity to produce valuable data with …

Abstract The International Mouse Phenoty** Consortium (IMPC; https://www.
mousephenotype. org/) web portal makes available curated, integrated and analysed …

The human genome encodes approximately 20,000 proteins, many still uncharacterised. It
has become clear that scientific research tends to focus on well-studied proteins, leading to …

Species persistence can be influenced by the amount, type, and distribution of diversity
across the genome, suggesting a potential relationship between historical demography and …

In biology and biomedicine, relating phenotypic outcomes with genetic variation and
environmental factors remains a challenge: patient phenotypes may not match known …

Deleterious mutations continuously accumulate in populations, building up a burden that
can threaten their survival, particularly in small populations when inbreeding exposes …

Despite progress in the development of standards for describing and exchanging scientific
information, the lack of easy-to-use standards for map** between different representations …

Associations between human genetic variation and clinical phenotypes have become a
foundation of biomedical research. Most repositories of these data seek to be disease …

Enhanced osteoclastogenesis and osteoclast activity contribute to the development of
osteoporosis, which is characterized by increased bone resorption and inadequate bone …