The rise of boron-containing compounds: advancements in synthesis, medicinal chemistry, and emerging pharmacology

RJ Grams, WL Santos, IR Scorei… - Chemical …, 2024 - ACS Publications
Boron-containing compounds (BCC) have emerged as important pharmacophores. To date,
five BCC drugs (including boronic acids and boroles) have been approved by the FDA for …

Carboranes in drug discovery, chemical biology and molecular imaging

A Marfavi, P Kavianpour, LM Rendina - Nature Reviews Chemistry, 2022 - nature.com
There exists a paucity of structural innovation and limited molecular diversity associated with
molecular frameworks in drug discovery and biomolecular imaging/chemical probe design …

Storing energy with molecular photoisomers

Z Wang, P Erhart, T Li, ZY Zhang, D Sampedro, Z Hu… - Joule, 2021 - cell.com
Some molecular photoisomers can be isomerized to a metastable high-energy state by
exposure to light. These molecules can then be thermally or catalytically converted back to …

Photoinduced Selective B–H Activation of nido-Carboranes

S Xu, H Zhang, J Xu, W Suo, CS Lu, D Tu… - Journal of the …, 2024 - ACS Publications
The development of new synthetic methods for B–H bond activation has been an important
research area in boron cluster chemistry, which may provide opportunities to broaden the …

Single─Not Double─3D-Aromaticity in an Oxidized Closo Icosahedral Dodecaiodo-Dodecaborate Cluster

J Poater, S Escayola, A Poater, F Teixidor… - Journal of the …, 2023 - ACS Publications
3D-aromatic molecules with (distorted) tetrahedral, octahedral, or spherical structures are
much less common than typical 2D-aromatic species or even 2D-aromatic-in-3D systems …

Biomimetic photodegradation of glyphosate in carborane-functionalized nanoconfined spaces

L Gan, MT Nord, JM Lessard, NQ Tufts… - Journal of the …, 2023 - ACS Publications
The removal of organophosphorus (OP) herbicides from water has been studied using
adsorptive removal, chemical oxidation, electrooxidation, enzymatic degradation, and …

Chemistry of three-dimensional icosahedral boron clusters anions: closo-dodecaborate (2-)[B12H12] 2-and carba-closo-dodecaborate (-)[CB11H12]-

L Wang, Y Jiang, S Duttwyler, F Lin, Y Zhang - Coordination Chemistry …, 2024 - Elsevier
Significant strides have been made in synthetic chemistry concerning icosahedral boron
clusters over the past decades, resulting in a proliferation of applications across various …

Direct B–H Functionalization of Icosahedral Carboranes via Hydrogen Atom Transfer

H Ren, P Zhang, J Xu, W Ma, D Tu, C Lu… - Journal of the American …, 2023 - ACS Publications
The efficient and selective functionalization of icosahedral carboranes (C2B10H12) at the
boron vertexes is a long-standing challenge owing to the presence of 10 inert B–H bonds in …

Boron cluster anions and their derivatives in complexation reactions

VV Avdeeva, EA Malinina, NT Kuznetsov - Coordination Chemistry Reviews, 2022 - Elsevier
Boron cluster anions attract the interest of chemists because of their electronic structures,
geometry, and chemical behavior. These weak coordinating ligands allow one to vary their …

Facile construction of new hybrid conjugation via boron cage extension

F Sun, S Tan, HJ Cao, C Lu, D Tu… - Journal of the …, 2023 - ACS Publications
Aromatic polycyclic systems have been extensively utilized as structural subunits for the
preparation of various functional molecules. Currently, aromatics-based polycyclic systems …