Atherosclerosis is an inflammatory disease of the large arteries that is the major cause of
cardiovascular disease (CVD) and stroke. Here, we review the current understanding of the …

Atherosclerosis, a dominant and growing cause of death and disability worldwide, involves
inflammation from its inception to the emergence of complications. Targeting inflammatory …

Atherosclerosis is the root cause of many cardiovascular diseases. Extensive research in
preclinical models and emerging evidence in humans have established the crucial roles of …

Obesity-related metabolic organ inflammation contributes to cardiometabolic disorders. In
obese individuals, changes in lipid fluxes and storage elicit immune responses in the …

Adult stem cells are important for mammalian tissues, where they act as a cell reserve that
supports normal tissue turnover and can mount a regenerative response following acute …

Aerobic exercise is associated with decreased cancer incidence and cancer-associated
mortality. However, little is known about the effects of exercise on pancreatic ductal …

Remarkable progress in ageing research has been achieved over the past decades.
General perceptions and experimental evidence pinpoint that the decline of physical …

Diet profoundly influences physiology. Whereas over-nutrition elevates risk for disease via
its influence on immunity and metabolism, caloric restriction and fasting appear to be …

Unresolved inflammation is a key mediator of advanced heart failure. Especially, damage,
pathogen, and lifestyle-associated molecular patterns are the major factors in initiating …

Exercise has long been known for its active role in improving physical fitness and sustaining
health. Regular moderate-intensity exercise improves all aspects of human health and is …