Abstract Analysis of clinical trial specimens such as formalin-fixed paraffin-embedded
(FFPE) tissue for molecular mechanisms of disease progression or drug response is often …

Breast cancer is a heterogeneous disease manifesting diversity at the molecular,
histological and clinical level. The development of breast cancer classification was centered …

Purpose: Molecular subty** for pancreatic cancer has made substantial progress in recent
years, facilitating the optimization of existing therapeutic approaches to improve clinical …

Background Although the tumor stroma in solid tumors like gastric cancer (GC) plays a
crucial role in chemo-resistance, specific targets to inhibit the interaction between the …

Purpose To evaluate the impact of the addition of bortezomib to rituximab,
cyclophosphamide, doxorubicin, vincristine, and prednisone (R-CHOP) on outcomes in …

Cancer is a genetic disease where genetic variations cause abnormally functioning genes
that appear to alter expression. Proteins, the final products of gene expression, determine …

Skeletal muscle macrophages participate in repair and regeneration following injury.
However, their role in physiological adaptations to exercise is unexplored. We determined …

DNA damage checkpoint kinases ATR and WEE1 are among key regulators of DNA
damage response pathways protecting cells from replication stress, a hallmark of cancer that …

High throughput genomic assays empower us to study the entire human genome in short
time with reasonable cost. Formalin fixed‐paraffin‐embedded (FFPE) tissue processing …

The aberrant expression and dysfunction of long non‐coding RNAs (lncRNAs) have been
identified as critical factors governing the initiation and progression of different human …