Deep learning with radiomics for disease diagnosis and treatment: challenges and potential

X Zhang, Y Zhang, G Zhang, X Qiu, W Tan, X Yin… - Frontiers in …, 2022 - frontiersin.org
The high-throughput extraction of quantitative imaging features from medical images for the
purpose of radiomic analysis, ie, radiomics in a broad sense, is a rapidly develo** and …

Artificial intelligence to identify genetic alterations in conventional histopathology

D Cifci, S Foersch, JN Kather - The Journal of pathology, 2022 - Wiley Online Library
Precision oncology relies on the identification of targetable molecular alterations in tumor
tissues. In many tumor types, a limited set of molecular tests is currently part of standard …

A large-scale synthetic pathological dataset for deep learning-enabled segmentation of breast cancer

K Ding, M Zhou, H Wang, O Gevaert, D Metaxas… - Scientific Data, 2023 - nature.com
The success of training computer-vision models heavily relies on the support of large-scale,
real-world images with annotations. Yet such an annotation-ready dataset is difficult to …

Prediction of DNA methylation-based tumor types from histopathology in central nervous system tumors with deep learning

DT Hoang, ED Shulman, R Turakulov, Z Abdullaev… - Nature Medicine, 2024 - nature.com
Precision in the diagnosis of diverse central nervous system (CNS) tumor types is crucial for
optimal treatment. DNA methylation profiles, which capture the methylation status of …

[HTML][HTML] Predicting gene mutation status via artificial intelligence technologies based on multimodal integration (MMI) to advance precision oncology

J Shao, J Ma, Q Zhang, W Li, C Wang - Seminars in cancer biology, 2023 - Elsevier
Personalized treatment strategies for cancer frequently rely on the detection of genetic
alterations which are determined by molecular biology assays. Historically, these processes …

Biological insights and novel biomarker discovery through deep learning approaches in breast cancer histopathology

D Mandair, JS Reis-Filho, A Ashworth - NPJ breast cancer, 2023 - nature.com
Breast cancer remains a highly prevalent disease with considerable inter-and intra-tumoral
heterogeneity complicating prognostication and treatment decisions. The utilization and …

A systematic pan-cancer study on deep learning-based prediction of multi-omic biomarkers from routine pathology images

S Arslan, J Schmidt, C Bass, D Mehrotra… - Communications …, 2024 - nature.com
Background The objective of this comprehensive pan-cancer study is to evaluate the
potential of deep learning (DL) for molecular profiling of multi-omic biomarkers directly from …

Pathology-and-genomics multimodal transformer for survival outcome prediction

K Ding, M Zhou, DN Metaxas, S Zhang - International Conference on …, 2023 - Springer
Survival outcome assessment is challenging and inherently associated with multiple clinical
factors (eg, imaging and genomics biomarkers) in cancer. Enabling multimodal analytics …

One label is all you need: Interpretable AI-enhanced histopathology for oncology

TE Tavolara, Z Su, MN Gurcan, MKK Niazi - Seminars in Cancer Biology, 2023 - Elsevier
Artificial Intelligence (AI)-enhanced histopathology presents unprecedented opportunities to
benefit oncology through interpretable methods that require only one overall label per …