Defining neonatal sepsis : Current Opinion in Pediatrics Defining neonatal sepsis : Current
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Background Antibiotics are used frequently in the neonatal intensive care unit. We aimed to
inform antibiotic stewardship strategies in a level 3 neonatal intensive care unit by …

Sepsis is a major cause of morbidity and mortality among infants in the NICU. Because
septic infants present with nonspecific clinical findings, providers are justifiably concerned …

Background Global assessment of antimicrobial agents prescribed to infants in the neonatal
intensive care unit (NICU) may inform antimicrobial stewardship efforts. Methods We …

Suspected neonatal sepsis is one of the most common diagnoses made in newborns (NBs),
but very few NBs actually have sepsis. There is no international consensus to clearly define …

Conclusions It is impossible to say with certainty that “culture-negative” sepsis does not
exist. Myriad observational data support the experience of an infant with clinical signs of …

Objective Determine risk of death or neurodevelopmental impairment (NDI) in infants with
late-onset sepsis (LOS) versus late-onset, antibiotic-treated, blood culture-negative …

Importance While most viral respiratory tract infections can be diagnosed clinically, clinicians
frequently order tests to identify the specific offending virus. While there has been …

Abstract Neonatal sepsis (NS) kills 750,000 infants every year. Effectively treating NS
requires timely diagnosis and antimicrobial therapy matched to the causative pathogens, but …

Neonatal infections continue to cause morbidity and mortality in infants. Among
approximately 400,000 infants followed nationally, the incidence rates of early-onset sepsis …