The immunopathogenesis of narcolepsy type 1
Abstract Narcolepsy type 1 (NT1) is a chronic sleep disorder resulting from the loss of a
small population of hypothalamic neurons that produce wake-promoting hypocretin (HCRT; …
small population of hypothalamic neurons that produce wake-promoting hypocretin (HCRT; …
HLA variation and SARS-CoV-2 specific antibody response
D Wolday, CYJ Fung, G Morgan, S Casalino… - Viruses, 2023 - mdpi.com
Differences in SARS-CoV-2-specific immune responses have been observed between
individuals following natural infection or vaccination. In addition to already known factors …
individuals following natural infection or vaccination. In addition to already known factors …
Genome-wide association studies of COVID-19 vaccine seroconversion and breakthrough outcomes in UK Biobank
Understanding the genetic basis of COVID-19 vaccine seroconversion is crucial to study the
role of genetics on vaccine effectiveness. In our study, we used UK Biobank data to find the …
role of genetics on vaccine effectiveness. In our study, we used UK Biobank data to find the …
Hypocortisolemic ASIA: a vaccine-and chronic infection-induced syndrome behind the origin of long COVID and myalgic encephalomyelitis
M Ruiz-Pablos, B Paiva, A Zabaleta - Frontiers in Immunology, 2024 - frontiersin.org
Myalgic encephalomyelitis or chronic fatigue syndrome (ME/CFS), long COVID (LC) and
post-COVID-19 vaccine syndrome show similarities in their pathophysiology and clinical …
post-COVID-19 vaccine syndrome show similarities in their pathophysiology and clinical …
Genome‐wide association studies of response and side effects to the BNT162b2 vaccine in Italian healthcare workers: Increased antibody levels and side effects in …
The remarkable variability of response to vaccines against SARS‐CoV‐2 is apparent. The
present study aims to estimate the extent to which the host genetic background contributes …
present study aims to estimate the extent to which the host genetic background contributes …
[HTML][HTML] Systems vaccinology studies–achievements and future potential
Human immune responses to vaccination are variable both within and between populations.
Systems vaccinology, which is the application of multi-omics technologies to vaccine …
Systems vaccinology, which is the application of multi-omics technologies to vaccine …
Lack of association between classical HLA genes and asymptomatic SARS-CoV-2 infection
A Marchal, ET Cirulli, I Neveux, E Bellos… - Human Genetics and …, 2024 - cell.com
Human genetic studies of critical COVID-19 pneumonia have revealed the essential role of
type I interferon-dependent innate immunity to SARS-CoV-2 infection. Conversely, an …
type I interferon-dependent innate immunity to SARS-CoV-2 infection. Conversely, an …
The humoral and cellular response to mRNA SARS‐CoV‐2 vaccine is influenced by HLA polymorphisms
FE Bertinetto, P Magistroni, GA Mazzola, C Costa… - HLA, 2023 - Wiley Online Library
Host genetic variability contributes to susceptibility to SARS‐CoV‐2 infection and COVID‐19
evolution and the role of HLA system has not clearly emerged, suggesting the involvement …
evolution and the role of HLA system has not clearly emerged, suggesting the involvement …
Genetic determinants of IgG antibody response to COVID-19 vaccination
Human humoral immune responses to SARS-CoV-2 vaccines exhibit substantial inter-
individual variability and have been linked to vaccine efficacy. To elucidate the underlying …
individual variability and have been linked to vaccine efficacy. To elucidate the underlying …
Baseline gut microbiota and metabolome predict durable immunogenicity to SARS-CoV-2 vaccines
The role of gut microbiota in modulating the durability of COVID-19 vaccine immunity is yet
to be characterised. In this cohort study, we collected blood and stool samples of 121 …
to be characterised. In this cohort study, we collected blood and stool samples of 121 …