The power and potential of mitochondria transfer
Mitochondria are believed to have originated through an ancient endosymbiotic process in
which proteobacteria were captured and co-opted for energy production and cellular …
which proteobacteria were captured and co-opted for energy production and cellular …
Mitochondrial transfer/transplantation: an emerging therapeutic approach for multiple diseases
Z Liu, Y Sun, Z Qi, L Cao, S Ding - Cell & bioscience, 2022 - Springer
Mitochondria play a pivotal role in energy generation and cellular physiological processes.
These organelles are highly dynamic, constantly changing their morphology, cellular …
These organelles are highly dynamic, constantly changing their morphology, cellular …
Comprehensive review of CRISPR-based gene editing: mechanisms, challenges, and applications in cancer therapy
M Chehelgerdi, M Chehelgerdi… - Molecular cancer, 2024 - Springer
The CRISPR system is a revolutionary genome editing tool that has the potential to
revolutionize the field of cancer research and therapy. The ability to precisely target and edit …
revolutionize the field of cancer research and therapy. The ability to precisely target and edit …
The functions, methods, and mobility of mitochondrial transfer between cells
Y Qin, X Jiang, Q Yang, J Zhao, Q Zhou… - Frontiers in oncology, 2021 - frontiersin.org
Mitochondria are vital organelles in cells, regulating energy metabolism and apoptosis.
Mitochondrial transcellular transfer plays a crucial role during physiological and pathological …
Mitochondrial transcellular transfer plays a crucial role during physiological and pathological …
Diversity in connexin biology
Over 35 years ago the cell biology community was introduced to connexins as the subunit
employed to assemble semicrystalline clusters of intercellular channels that had been well …
employed to assemble semicrystalline clusters of intercellular channels that had been well …
Connexin43 promotes exocytosis of damaged lysosomes through actin remodelling
N Domingues, S Catarino, B Cristóvão… - The EMBO …, 2024 - embopress.org
A robust and efficient cellular response to lysosomal membrane damage prevents leakage
from the lysosome lumen into the cytoplasm. This response is understood to happen through …
from the lysosome lumen into the cytoplasm. This response is understood to happen through …
[HTML][HTML] Optimizing CRISPR/Cas9 precision: Mitigating off-target effects for safe integration with photodynamic and stem cell therapies in cancer treatment
CRISPR/Cas9 precision genome editing has revolutionized cancer treatment by introducing
specific alterations to the cancer genome. But the therapeutic potential of CRISPR/Cas9 is …
specific alterations to the cancer genome. But the therapeutic potential of CRISPR/Cas9 is …
Breast cancers that disseminate to bone marrow acquire aggressive phenotypes through CX43-related tumor-stroma tunnels
Estrogen receptor-positive (ER+) breast cancer commonly disseminates to bone marrow,
where interactions with mesenchymal stromal cells (MSCs) shape disease trajectory. We …
where interactions with mesenchymal stromal cells (MSCs) shape disease trajectory. We …
Tunneling nanotubes: The intercellular conduits contributing to cancer pathogenesis and its therapy
Tunneling nanotubes (TNTs) are intercellular conduits, which meet the communication
needs of non-adjacent cells situated in the same tissue but at distances up to a few hundred …
needs of non-adjacent cells situated in the same tissue but at distances up to a few hundred …
Static magnetic field-modulated mesenchymal stem cell-derived mitochondria-containing microvesicles for enhanced intervertebral disc degeneration therapy
P Shi, H Gao, Z Cheng, K Zhao, Y Chen… - Journal of …, 2024 - Springer
Intervertebral disc degeneration (IVDD) is characterized by the senescence and declining
vitality of nucleus pulposus cells (NPCs), often driven by mitochondrial dysfunction. This …
vitality of nucleus pulposus cells (NPCs), often driven by mitochondrial dysfunction. This …