Paradigm shift in the treatment options of hepatocellular carcinoma

TH Su, SJ Hsu, JH Kao - Liver International, 2022 - Wiley Online Library
Hepatocellular carcinoma (HCC) is prevalent worldwide with suboptimal therapeutic
outcomes. The advancement of therapeutic options and the development of new systemic …

SBRT for HCC: Overview of technique and treatment response assessment

KL Shampain, CE Hackett, S Towfighi, A Aslam… - Abdominal …, 2021 - Springer
Stereotactic body radiation therapy (SBRT) is an emerging locoregional treatment (LRT)
modality used in the management of patients with hepatocellular carcinoma (HCC). The …

Assessment of organ doses from head and neck cone-beam computed tomography (CBCT) in adaptive radiation therapy: A phantom study

S Paduka, S Thongsawad, P Janthawanno… - Radiation Physics and …, 2024 - Elsevier
The purpose of this study was to estimate accumulated organ doses from cone-beam
computed tomography (CBCT) in adaptive radiation therapy (ART) of head and neck cancer …

A human-in-the-loop based Bayesian network approach to improve imbalanced radiation outcomes prediction for hepatocellular cancer patients with stereotactic body …

Y Luo, KC Cuneo, TS Lawrence, MM Matuszak… - Frontiers in …, 2022 - frontiersin.org
Background Imbalanced outcome is one of common characteristics of oncology datasets.
Current machine learning approaches have limitation in learning from such datasets. Here …

Role of Stereotactic Body Radiation Therapy in Hepatocellular Carcinoma

AY Abualnil, R Kumar, MA George… - Surgical Oncology …, 2024 - surgonc.theclinics.com
Stereotactic body radiation therapy (SBRT) is a promising treatment option for patients with
hepatocellular carcinoma (HCC), the most common type of primary liver cancer. 1 This …

Clinical impact of carbon‐ion radiotherapy on hepatocellular carcinoma with Child‐Pugh B cirrhosis

Y Hiroshima, M Wakatsuki, T Kaneko… - Cancer …, 2023 - Wiley Online Library
Abstract Background and Aims Hepatocellular carcinoma (HCC) patients with Child‐Pugh
(CP)‐B not eligible for surgery nor other focal therapy options due to impaired liver function …

Role of functional MRI in liver SBRT: Current use and future directions

S Tadimalla, W Wang, A Haworth - Cancers, 2022 - mdpi.com
Simple Summary The use of magnetic resonance imaging (MRI) for liver radiation treatment
planning, adaptation and response assessment is an active area of clinical research …

Non-classic radiation-induced liver disease after intensity-modulated radiotherapy for Child–Pugh grade B patients with locally advanced hepatocellular carcinoma

JX Li, RJ Zhang, MQ Qiu, LY Yan, ML He, MY Long… - Radiation …, 2023 - Springer
Background The incidence of classic radiation-induced liver disease (cRILD) has been
significantly reduced. However, non-classic radiation-induced liver disease (ncRILD) …

[HTML][HTML] TNFR1 and the TNFα axis as a targetable mediator of liver injury from stereotactic body radiation therapy

MM Cousins, E Morris, C Maurino, TP Devasia… - Translational …, 2021 - Elsevier
Introduction Radiation therapy for the management of intrahepatic malignancies can
adversely affect liver function. Liver damage has been associated with increased levels of …

A Phase II Study of Optimized Individualized Adaptive Radiotherapy for Hepatocellular Carcinoma

DJ Herr, C Wang, M Mendiratta-Lala, M Matuszak… - Clinical Cancer …, 2023 - AACR
Purpose: We hypothesized that optimizing the utility of stereotactic body radiotherapy
(SBRT) based on the individual patient's probability for tumor control and risk of liver injury …