Myosin motors power movements on actin filaments, whereas dynein and kinesin motors
power movements on microtubules. The mechanisms of these motor proteins differ, but, in …

Transport phenomena in spatially periodic systems far from thermal equilibrium are
considered. The main emphasis is put on directed transport in so-called Brownian motors …

Dynamic measurements of molecular machines can provide invaluable insights into their
mechanism, but these measurements have been challenging in living cells. Here, we …

Pumps and motors are essential components of the world as we know it. From the complex
proteins that sustain our cells, to the mechanical marvels that power industries, much we …

Optical tweezers are devices that use a single, strongly focused laser beam for the remote,
noncontact trap** and manipulation of microscopic objects. Since the first demonstration …

One of the major challenges in modern biology is to understand how the molecular
components of a living cell operate in a highly noisy environment. What are the specific …

The dynamic behaviour of myosin V molecules translocating along actin filaments has been
mainly studied by optical microscopy. The processive hand-over-hand movement coupled …

Physical Biology of the Cell is a textbook for a first course in physical biology or biophysics
for undergraduate or graduate students. It maps the huge and complex landscape of cell …

Myosin V is a dimeric molecular motor that moves processively on actin, with the center of
mass moving∼ 37 nanometers for each adenosine triphosphate hydrolyzed. We have …

The microtubule-based kinesin motors and actin-based myosin motors generate motions
associated with intracellular trafficking, cell division, and muscle contraction. Early studies …