Multiscale simulations of biological membranes: the challenge to understand biological phenomena in a living substance
Biological membranes are tricky to investigate. They are complex in terms of molecular
composition and structure, functional over a wide range of time scales, and characterized by …
composition and structure, functional over a wide range of time scales, and characterized by …
Phospholipids and cholesterol: Inducers of cancer multidrug resistance and therapeutic targets
Lipids, phospholipids and cholesterol in particular, are the predominant components of the
plasma membrane, wherein multidrug efflux transporters of the ATP-binding cassette (ABC) …
plasma membrane, wherein multidrug efflux transporters of the ATP-binding cassette (ABC) …
Folding and misfolding of human membrane proteins in health and disease: from single molecules to cellular proteostasis
Advances over the past 25 years have revealed much about how the structural properties of
membranes and associated proteins are linked to the thermodynamics and kinetics of …
membranes and associated proteins are linked to the thermodynamics and kinetics of …
[HTML][HTML] Historical review of computer simulation of radiation effects in materials
K Nordlund - Journal of Nuclear Materials, 2019 - Elsevier
In this Article, I review the development of computer simulation techniques for studying
radiation effects in materials from 1946 until 2018. These developments were often closely …
radiation effects in materials from 1946 until 2018. These developments were often closely …
[HTML][HTML] Biosurfactants and surfactants interacting with membranes and proteins: same but different?
DE Otzen - Biochimica et Biophysica Acta (BBA)-Biomembranes, 2017 - Elsevier
Biosurfactants (BS) are surface-active molecules produced by microorganisms. For several
decades they have attracted interest as promising alternatives to current petroleum-based …
decades they have attracted interest as promising alternatives to current petroleum-based …
Hopanoid lipids: from membranes to plant–bacteria interactions
Lipid research represents a frontier for microbiology, as showcased by hopanoid lipids.
Hopanoids, which resemble sterols and are found in the membranes of diverse bacteria …
Hopanoids, which resemble sterols and are found in the membranes of diverse bacteria …
Differential scanning calorimetry: An invaluable tool for a detailed thermodynamic characterization of macromolecules and their interactions
MH Chiu, EJ Prenner - Journal of Pharmacy and Bioallied …, 2011 - journals.lww.com
Abstract Differential Scanning Calorimetry (DSC) is a highly sensitive technique to study the
thermotropic properties of many different biological macromolecules and extracts. Since its …
thermotropic properties of many different biological macromolecules and extracts. Since its …
The amphiphilic nature of saponins and their effects on artificial and biological membranes and potential consequences for red blood and cancer cells
JH Lorent, J Quetin-Leclercq… - Organic & biomolecular …, 2014 - pubs.rsc.org
Saponins, amphiphiles of natural origin with numerous biological activities, are widely used
in the cosmetic and pharmaceutical industry. Some saponins exhibit relatively selective …
in the cosmetic and pharmaceutical industry. Some saponins exhibit relatively selective …
Quantitative comparison against experiments reveals imperfections in force fields' descriptions of popc–cholesterol interactions
Cholesterol is a central building block in biomembranes, where it induces orientational
order, slows diffusion, renders the membrane stiffer, and drives domain formation. Molecular …
order, slows diffusion, renders the membrane stiffer, and drives domain formation. Molecular …
[HTML][HTML] Membrane-attached mammalian cytochromes P450: An overview of the membrane's effects on structure, drug binding, and interactions with redox partners
Mammalian cytochromes P450 are an important class of enzymes involved in the
biotransformation of many endo-and exogenous compounds. Cytochrome P450 isoforms …
biotransformation of many endo-and exogenous compounds. Cytochrome P450 isoforms …