Bone biomaterials and interactions with stem cells
Bone biomaterials play a vital role in bone repair by providing the necessary substrate for
cell adhesion, proliferation, and differentiation and by modulating cell activity and function. In …
cell adhesion, proliferation, and differentiation and by modulating cell activity and function. In …
Amorphous solid dispersions and nanocrystal technologies for poorly water-soluble drug delivery–an update
Poor water-solubility remains a typical property of drug candidates in pharmaceutical
development pipelines today. Various processes have been developed to increase the …
development pipelines today. Various processes have been developed to increase the …
Organoids—preclinical models of human disease
Organoids—Preclinical Models of Disease An organoid is a three-dimensional construct
composed of multiple cell types that originates from stem cells through self-organization and …
composed of multiple cell types that originates from stem cells through self-organization and …
3D Printing technologies for drug delivery: a review
With the FDA approval of the first 3D printed tablet, Spritam®, there is now precedence set
for the utilization of 3D printing for the preparation of drug delivery systems. The capabilities …
for the utilization of 3D printing for the preparation of drug delivery systems. The capabilities …
3D bioprinting for drug discovery and development in pharmaceutics
Successful launch of a commercial drug requires significant investment of time and financial
resources wherein late-stage failures become a reason for catastrophic failures in drug …
resources wherein late-stage failures become a reason for catastrophic failures in drug …
3D-printed ABS and PLA scaffolds for cartilage and nucleus pulposus tissue regeneration
Painful degeneration of soft tissues accounts for high socioeconomic costs. Tissue
engineering aims to provide biomimetics recapitulating native tissues. Biocompatible …
engineering aims to provide biomimetics recapitulating native tissues. Biocompatible …
Current trends in the design of scaffolds for computer-aided tissue engineering
Advances introduced by additive manufacturing have significantly improved the ability to
tailor scaffold architecture, enhancing the control over microstructural features. This has led …
tailor scaffold architecture, enhancing the control over microstructural features. This has led …
A brief review of extrusion‐based tissue scaffold bio‐printing
Extrusion‐based bio‐printing has great potential as a technique for manipulating
biomaterials and living cells to create three‐dimensional (3D) scaffolds for damaged tissue …
biomaterials and living cells to create three‐dimensional (3D) scaffolds for damaged tissue …
Extrusion and microfluidic‐based bioprinting to fabricate biomimetic tissues and organs
Next generation engineered tissue constructs with complex and ordered architectures aim to
better mimic the native tissue structures, largely due to advances in 3D bioprinting …
better mimic the native tissue structures, largely due to advances in 3D bioprinting …
Bone tissue engineering scaffolding: computer-aided scaffolding techniques
Tissue engineering is essentially a technique for imitating nature. Natural tissues consist of
three components: cells, signalling systems (eg growth factors) and extracellular matrix …
three components: cells, signalling systems (eg growth factors) and extracellular matrix …