Environmental toxicology and ecotoxicology research efforts are employing proteomics with
fish models as New Approach Methodologies, along with in silico, in vitro and other omics …

Immunohistochemistry (IHC) is still widely used as a morphology-based assay for in situ
analysis of target proteins as specific tumor antigens. However, as a very heterogeneous …

Voluntary striated muscles are characterized by a highly complex and dynamic proteome
that efficiently adapts to changed physiological demands or alters considerably during …

Hepatocytes work in highly structured, repetitive hepatic lobules. Blood flow across the
radial axis of the lobule generates oxygen, nutrient, and hormone gradients, which result in …

Metal‐organic frameworks (MOFs) have the potential to revolutionize the biotechnological
and medical landscapes due to their easily tunable crystalline porous structure. Herein, the …

The imaging of biological tissues can offer valuable information about the sample
composition, which improves the understanding of analyte distribution in such complex …

Studying cell heterogeneity can provide a deeper understanding of biological activities, but
appropriate studies cannot be performed using traditional bulk analysis methods. The …

Metal ions are the center of an important class of therapeutics, ie metallodrugs for their
unique coordination geometries and redox states. Many cellular functions depend on the …

The extracellular vesicles (EVs) released by cells play a crucial role in intercellular
communications and interactions. The direct shedding of EVs from the plasma membrane …

Breast cancer (BC) is one of the most heterogeneous groups of cancer. As every biotype of
BC is unique and presents a particular “omic” signature, they are increasingly characterized …