A Review of the Phytochemistry and Pharmacology of Phyllanthus urinaria L.

M Geethangili, ST Ding - Frontiers in pharmacology, 2018 - frontiersin.org
The genus Phyllanthus (L.) is one of the most important groups of plants belonging to the
Phyllantaceae family. Phyllanthus urinaria (L.) is an annual perennial herbal species found …

Inhibitory activities of grape bioactive compounds against enzymes linked with human diseases

V Dwibedi, S Jain, D Singhal, A Mittal, SK Rath… - Applied microbiology …, 2022 - Springer
A quest for identification of novel, safe and efficient natural compounds, as additives in the
modern food and cosmetic industries, has been prompted by concerns about toxicity and …

Bio-oriented synthesis of novel polyhydroquinoline derivatives as α-glucosidase inhibitor for management of diabetes

F Talab, S Ullah, A Alam, SA Halim, NU Rehman… - ACS …, 2023 - ACS Publications
Polyhydroquinoline derivatives (1-15) were synthesized through an unsymmetrical Hantzsch
reaction in excellent yields by treating 3, 5-dibromo-4-hydroxybenzaldehyde, dimedone …

Design, synthesis, spectroscopic characterization, single crystal X-ray analysis, in vitro α-amylase inhibition assay, DPPH free radical evaluation and computational …

M Devi, P Kumar, R Singh, J Sindhu… - European Journal of …, 2023 - Elsevier
In our quest to design and develop N/O-containing inhibitors of α-amylase, we have tried to
synergize the inhibitory action of 1, 4-naphthoquinone, imidazole and 1, 2, 3-triazole motifs …

[HTML][HTML] Alpha glucosidase inhibitors

M Akmal, P Patel, R Wadhwa - StatPearls [internet], 2024 - ncbi.nlm.nih.gov
Alpha Glucosidase Inhibitors - StatPearls - NCBI Bookshelf US flag An official website of the
United States government Here's how you know NIH NLM Logo Access keys NCBI Homepage …

Antidiabetic potential of novel 1, 3, 5-trisubstituted-2-thioxoimidazloidin-4-one analogues: Insights into α-glucosidase, α-amylase, and antioxidant activities

SM Khirallah, HMM Ramadan, HAA Aladl, NO Ayaz… - Pharmaceuticals, 2022 - mdpi.com
As the ninth leading cause of death globally, diabetes mellitus (DM) is considered to be the
worst chronic metabolic disease requiring an enormous need for healthcare with over 578 …

Design, synthesis and antidiabetic study of triazole clubbed indole derivatives as α-glucosidase inhibitors

P Sharma, GD Gupta, V Asati - Bioorganic Chemistry, 2023 - Elsevier
Abstract α-Glucosidase is an enzyme present near the brush boundary of the small intestine
that is essential in the hydrolysis of carbohydrates to glucose. Because inhibiting this …

Combination therapy of bioactive compounds with acarbose: A proposal to control hyperglycemia in type 2 diabetes

JJ Uuh Narvaez… - Journal of Food …, 2022 - Wiley Online Library
Abstract Type 2 diabetes (T2D) is a chronic metabolic disease with a high impact on public
health and social welfare. Hyperglycemia is a characteristic of T2D that leads to different …

A review of antidiabetic active thiosugar sulfoniums, salacinol and neokotalanol, from plants of the genus Salacia

T Morikawa, K Ninomiya, G Tanabe, H Matsuda… - Journal of natural …, 2021 - Springer
During our studies characterizing functional substances from food resources for the
prevention and treatment of lifestyle-related diseases, we isolated the active constituents …

Therapeutic potential of seaweed-derived bioactive compounds for cardiovascular disease treatment

CH Cho, YA Lu, MY Kim, YJ Jeon, SH Lee - Applied Sciences, 2022 - mdpi.com
Cardiovascular diseases are closely related to hypertension, type 2 diabetes mellitus,
obesity, and hyperlipidemia. Many studies have reported that an unhealthy diet and …