Mitochondrial dysfunction is widely implicated in various human diseases, through
mechanisms that go beyond mitochondria's well-established role in energy generation …

Mitochondria are well known as 'the powerhouses of the cell'. Indeed, their major role is
cellular energy production driven by both mitochondrial and nuclear DNA. Such a feature …

In mammalian ovaries, oocytes are physically coupled to somatic granulosa cells, and this
coupling is crucial for the growth and development of competent oocytes as it mediates the …

The development of oocytes and early embryos is dependent on mitochondrial ATP
production. This reliance on mitochondrial activity, together with the exclusively maternal …

Mitochondria plays an essential role in regulating cellular metabolic homeostasis,
proliferation/differentiation, and cell death. Mitochondrial dysfunction is implicated in many …

Mitochondria have a crucial role in cellular function and exhibit remarkable plasticity,
adjusting both their structure and activity to meet the changing energy demands of a cell …

Germ cell formation and embryonic development require ATP synthesized by mitochondria.
The dynamic system of the mitochondria, and in particular, the fusion of mitochondria, are …

Follicular microenvironment is paramount in the acquisition of oocyte competence, which is
dependent on two interconnected and interdependent processes: nuclear and cytoplasmic …

The mitochondria are responsible for the production of cellular ATP, the regulation of
cytosolic calcium levels, and the organization of numerous apoptotic proteins through the …

Mitochondrial dysfunction plays a crucial role in the pathological physiology of polycystic
ovary syndrome (PCOS). Mitochondrial quality control system is vital to maintaining …