Polycyclic polyprenylated acylphloroglucinols (PPAPs) are a class of hybrid natural products
sharing the mevalonate/methylerythritol phosphate and polyketide biosynthetic pathways …

Plants of the genus Hypericum (Hypericaceae) are used in folk medicine all over the world,
H. perforatum being the most well-known species. Standardized extracts of this plant are …

This review is dedicated to the comparative analysis of structure-activity relationships for
more than 75 natural and synthetic derivatives of adamantane. Some of these compounds …

Bicyclic polyprenylated acylphloroglucinols (BPAPs), the principal bioactive benzophenone
products isolated from plants of genera Garcinia and Hypericum, have attracted noticeable …

The new polyprenylated acylphloroglucinol derivatives 1–15 and the known furohyperforin
(16) were isolated from the stems and leaves of Hypericum perforatum. Their structures were …

Ethnopharmacological relevance Chronic inflammation has an important role in the
development of cancers. Hypericum sampsonii, known as “Yuanbao Cao”, is mainly …

Three new compounds, 4-geranyloxy-2-hydroxy-6-isoprenyloxybenzophenone (1),
hypericumone A (2) and hypericumone B (3), were obtained from the aerial parts of …

Hypericum is a widely present plant, and extracts of its leaves, flowers, and aerial elements
have been employed for many years as therapeutic cures for depression, skin wounds, and …

Chemical investigation of the aerial parts of Hypericum sampsonii led to the isolation of
seven new polycyclic polyprenylated acylphloroglucinols, hypersampsonones A–G (1–7) …

Chemical investigation of the extracts of the aerial parts of Hypericum przewalskii Maxim.
resulted in the isolation and identification of six new epoxychromene-containing polycyclic …