High-grade serous ovarian cancer: basic sciences, clinical and therapeutic standpoints
MA Lisio, L Fu, A Goyeneche, Z Gao… - International journal of …, 2019 - mdpi.com
Among a litany of malignancies affecting the female reproductive tract, that of the ovary is the
most frequently fatal. Moreover, while the steady pace of scientific discovery has fuelled …
most frequently fatal. Moreover, while the steady pace of scientific discovery has fuelled …
[HTML][HTML] Epidemiology of ovarian cancer: a review
BM Reid, JB Permuth, TA Sellers - Cancer biology & medicine, 2017 - ncbi.nlm.nih.gov
Ovarian cancer (OC) is the seventh most commonly diagnosed cancer among women in the
world and the tenth most common in China. Epithelial OC is the most predominant …
world and the tenth most common in China. Epithelial OC is the most predominant …
Ovarian cancer statistics, 2018
In 2018, there will be approximately 22,240 new cases of ovarian cancer diagnosed and
14,070 ovarian cancer deaths in the United States. Herein, the American Cancer Society …
14,070 ovarian cancer deaths in the United States. Herein, the American Cancer Society …
Cancer Risks Associated With Germline PALB2 Pathogenic Variants: An International Study of 524 Families
X Yang, G Leslie, A Doroszuk, S Schneider… - Journal of clinical …, 2020 - ascopubs.org
PURPOSE To estimate age-specific relative and absolute cancer risks of breast cancer and
to estimate risks of ovarian, pancreatic, male breast, prostate, and colorectal cancers …
to estimate risks of ovarian, pancreatic, male breast, prostate, and colorectal cancers …
Germline and somatic tumor testing in epithelial ovarian cancer: ASCO guideline
PA Konstantinopoulos, B Norquist… - Journal of Clinical …, 2020 - ascopubs.org
PURPOSE To provide recommendations on genetic and tumor testing for women diagnosed
with epithelial ovarian cancer based on available evidence and expert consensus …
with epithelial ovarian cancer based on available evidence and expert consensus …
BRCA mutations in ovarian and prostate cancer: bench to bedside
Simple Summary DNA damage is one of the hallmarks of cancer. Epithelial ovarian cancer
(EOC)—especially the high-grade serous subtype—harbors a defect in at least one DNA …
(EOC)—especially the high-grade serous subtype—harbors a defect in at least one DNA …
Management of hereditary breast cancer: American society of clinical oncology, American society for radiation oncology, and society of surgical oncology guideline
NM Tung, JC Boughey, LJ Pierce… - Journal of clinical …, 2020 - ascopubs.org
PURPOSE To develop recommendations for management of patients with breast cancer
(BC) with germline mutations in BC susceptibility genes. METHODS The American Society …
(BC) with germline mutations in BC susceptibility genes. METHODS The American Society …
Epidemiology of epithelial ovarian cancer
Highlights•Ovarian cancer is a major cause of mortality and case numbers are
increasing.•Five-year relative survival is below 45%.•Reproductive exposures strongly …
increasing.•Five-year relative survival is below 45%.•Reproductive exposures strongly …
Epithelial ovarian cancer: providing evidence of predisposition genes
S Shah, A Cheung, M Kutka, M Sheriff… - International Journal of …, 2022 - mdpi.com
Epithelial ovarian cancer (EOC) is one of the cancers most influenced by hereditary factors.
A fourth to a fifth of unselected EOC patients carry pathogenic variants (PVs) in a number of …
A fourth to a fifth of unselected EOC patients carry pathogenic variants (PVs) in a number of …
Inherited mutations in women with ovarian carcinoma
Importance Germline mutations inBRCA1andBRCA2are relatively common in women with
ovarian, fallopian tube, and peritoneal carcinoma (OC) causing a greatly increased lifetime …
ovarian, fallopian tube, and peritoneal carcinoma (OC) causing a greatly increased lifetime …