Breast cancer is the most frequent malignancy in females. Due to its major impact on
population, this disease represents a critical public health problem that requires further …

The generation of new lymphatic vessels through lymphangiogenesis and the remodelling
of existing lymphatics are thought to be important steps in cancer metastasis. The past …

Blood and lymphatic vessels form a versatile transport network and provide inductive signals
to regulate tissue-specific functions. Blood vessels in bone regulate osteogenesis and …

Deregulation of angiogenesis–the growth of new blood vessels from an existing vasculature–
is a main driving force in many severe human diseases including cancer. As such, tumor …

Metastasis is the leading cause of cancer mortality. The metastatic cascade represents a
multi-step process which includes local tumor cell invasion, entry into the vasculature …

Fibroblasts have exceptional phenotypic plasticity and capability to secrete vast amount of
soluble factors, extracellular matrix components and extracellular vesicles. While in …

Angiogenesis is a hallmark of wound healing, the menstrual cycle, cancer, and various
ischemic and inflammatory diseases. A rich variety of pro-and antiangiogenic molecules …

In salt-sensitive hypertension, the accumulation of Na+ in tissue has been presumed to be
accompanied by a commensurate retention of water to maintain the isotonicity of body fluids …

Kaposiform hemangioendothelioma (KHE) is a rare vascular neoplasm with high morbidity
and mortality. The initiating mechanism during the pathogenesis of KHE has yet to be …

Thyroid cancer (TC) is the eighth most frequently diagnosed cancer worldwide with a rising
incidence in the past 20 years. Surgery is the primary strategy of therapy for patients with …