Bioactive luminescent transition‐metal complexes for biomedical applications

DL Ma, HZ He, KH Leung, DSH Chan… - Angewandte Chemie …, 2013 - Wiley Online Library
The serendipitous discovery of the anticancer drug cisplatin cemented medicinal inorganic
chemistry as an independent discipline in the 1960s. Luminescent metal complexes have …

DNA-based asymmetric catalysis

AJ Boersma, RP Megens, BL Feringa… - Chemical Society …, 2010 - pubs.rsc.org
The unique chiral structure of DNA has been a source of inspiration for the development of a
new class of bio-inspired catalysts. The novel concept of DNA-based asymmetric catalysis …

A dual-emission fluorescent nanocomplex of gold-cluster-decorated silica particles for live cell imaging of highly reactive oxygen species

T Chen, Y Hu, Y Cen, X Chu, Y Lu - Journal of the American …, 2013 - ACS Publications
A novel nanocomplex displaying single-excitation and dual-emission fluorescent properties
has been developed through a crown-like assembly of dye-encapsulated silica particles …

Recent developments in oligonucleotide conjugation

Y Singh, P Murat, E Defrancq - Chemical Society Reviews, 2010 - pubs.rsc.org
Synthetic oligonucleotides (ONs) are being investigated for various therapeutic and
diagnostic applications. The interest in ONs arises because of their capability to cause …

Toward the development of metal-based synthetic nucleases: DNA binding and oxidative DNA cleavage of a mixed copper (II) complex with N-(9H-purin-6-yl) …

JL García-Giménez, M González-Álvarez… - Journal of inorganic …, 2009 - Elsevier
The complex [Cu (N9-ABS)(phen) 2]· 3.6 H2O, H2N9-ABS= N-(9H-purin-6-yl)
benzenesulfonamide and phen= 1, 10-phenanthroline, has been synthesized and then …

The coordination chemistry of N-heterocyclic carboxylic acid: A comparison of the coordination polymers constructed by 4, 5-imidazoledicarboxylic acid and 1H-1, 2, 3 …

S Zhang, W Shi, P Cheng - Coordination Chemistry Reviews, 2017 - Elsevier
In recent decades, coordination polymers (CPs) constructed by metal ions/clusters as nodes
and organic linkers through coordination interactions, have expanded rapidly in both …

Progress in artificial metallonucleases

F Mancin, P Scrimin, P Tecilla - Chemical Communications, 2012 - pubs.rsc.org
The development of synthetic agents able to hydrolytically cleave DNA with high efficiency
and selectivity is still a fascinating challenge. Over the years, many examples have been …

Structure-activity relationships of new Organotin (IV) anticancer agents and their cytotoxicity profile on HL-60, MCF-7 and HeLa human cancer cell lines

H Ullah, V Previtali, HB Mihigo, B Twamley… - European Journal of …, 2019 - Elsevier
There is a growing interest in the cancer cell growth inhibitory effects of organotin (IV)
compounds and, accordingly, a new series of dimethyl-, di-(n-butyl)-, diphenyl-and chloro …

Artificial metalloenzymes as selective catalysts in aqueous media

J Steinreiber, TR Ward - Coordination Chemistry Reviews, 2008 - Elsevier
The fusion of homogeneous and enzymatic catalysis has recently drawn attention due to
reported novel activities and high selectivities. The incorporation of metal-catalysts into …

Potential photoactivated metallopharmaceuticals: from active molecules to supported drugs

D Crespy, K Landfester, US Schubert… - Chemical …, 2010 - pubs.rsc.org
Apart from cisplatin and some derivatives successful metallopharmaceuticals are still scarce
in antitumour therapy. Although novel metal complexes have been investigated in preclinical …