Amyloid‐β PET in Alzheimer's disease: A systematic review and Bayesian meta‐analysis

D Ruan, L Sun - Brain and Behavior, 2023 - Wiley Online Library
Background In recent years, longitudinal studies of Alzheimer's disease (AD) have been
successively concluded. Our aim is to determine the efficacy of amyloid‐β (Aβ) PET in …

Association between midlife vascular risk factors and estimated brain amyloid deposition

RF Gottesman, ALC Schneider, Y Zhou, J Coresh… - Jama, 2017 - jamanetwork.com
Importance Midlife vascular risk factors have been associated with late-life dementia.
Whether these risk factors directly contribute to brain amyloid deposition is less well …

Clinical validity of increased cortical uptake of amyloid ligands on PET as a biomarker for Alzheimer's disease in the context of a structured 5-phase development …

K Chiotis, L Saint-Aubert, M Boccardi, A Gietl… - Neurobiology of …, 2017 - Elsevier
The use of biomarkers has been proposed for diagnosing Alzheimer's disease in recent
criteria, but some biomarkers have not been sufficiently investigated to justify their routine …

Regional brain hypometabolism is unrelated to regional amyloid plaque burden

A Altmann, B Ng, SM Landau, WJ Jagust, MD Greicius - Brain, 2015 - academic.oup.com
Abstract See Sorg and Grothe (doi: 10.1093/brain/awv302) for a scientific commentary on
this article. In its original form, the amyloid cascade hypothesis of Alzheimer's disease holds …

Non-white matter tissue extraction and deep convolutional neural network for Alzheimer's disease detection

TD Vu, NH Ho, HJ Yang, J Kim, HC Song - Soft Computing, 2018 - Springer
In this paper, we introduce an automatic and robust method to detect and identify
Alzheimer's disease (AD) using the magnetic resonance imaging (MRI) and positron …

Spatial normalization and quantification approaches of PET imaging for neurological disorders

T Zhang, S Wu, X Zhang, Y Dai, A Wang… - European Journal of …, 2022 - Springer
Quantification approaches of positron emission tomography (PET) imaging provide user-
independent evaluation of pathophysiological processes in living brains, which have been …

Regional brain amyloid-β accumulation associates with domain-specific cognitive performance in Parkinson disease without dementia

RS Akhtar, SX **e, YJ Chen, J Rick, RG Gross… - PLoS …, 2017 - journals.plos.org
Parkinson disease patients develop clinically significant cognitive impairment at variable
times over their disease course, which is often preceded by milder deficits in memory, visuo …

Association of intracranial atherosclerotic disease with brain β-amyloid deposition: secondary analysis of the ARIC study

RF Gottesman, TH Mosley, DS Knopman, Q Hao… - JAMA …, 2020 - jamanetwork.com
Importance Intracranial atherosclerotic disease (ICAD) is an important cause of stroke and
has also been recently identified as an important risk factor for all-cause dementia, but the …

Automated PET-only quantification of amyloid deposition with adaptive template and empirically pre-defined ROI

G Akamatsu, Y Ikari, A Ohnishi, H Nishida… - Physics in Medicine …, 2016 - iopscience.iop.org
Amyloid PET is useful for early and/or differential diagnosis of Alzheimer's disease (AD).
Quantification of amyloid deposition using PET has been employed to improve diagnosis …

Evaluation of software tools for automated identification of neuroanatomical structures in quantitative β-amyloid PET imaging to diagnose Alzheimer's disease

T Tuszynski, M Rullmann, J Luthardt, D Butzke… - European journal of …, 2016 - Springer
Introduction For regional quantification of nuclear brain imaging data, defining volumes of
interest (VOIs) by hand is still the gold standard. As this procedure is time-consuming and …