Advances in our understanding of the molecular mechanisms of action of cisplatin in cancer therapy

PB Tchounwou, S Dasari, FK Noubissi… - Journal of …, 2021 - Taylor & Francis
Cisplatin and other platinum-based chemotherapeutic drugs have been used extensively for
the treatment of human cancers such as bladder, blood, breast, cervical, esophageal, head …

ROS stress in cancer cells and therapeutic implications

H Pelicano, D Carney, P Huang - Drug resistance updates, 2004 - Elsevier
Reactive oxygen species (ROS) are constantly generated and eliminated in the biological
system, and play important roles in a variety of normal biochemical functions and abnormal …

Oxidant signals and oxidative stress

T Finkel - Current opinion in cell biology, 2003 - Elsevier
Although oxidants clearly possess the capacity to behave in a random and destructive
fashion, growing evidence suggests that in many instances the production of reactive …

A review of the interaction among dietary antioxidants and reactive oxygen species

HE Seifried, DE Anderson, EI Fisher… - The Journal of nutritional …, 2007 - Elsevier
During normal cellular activities, various processes inside of cells produce reactive oxygen
species (ROS). Some of the most common ROS are hydrogen peroxide (H2O2), superoxide …

The Mechanism of Antifungal Action of Essential Oil from Dill (Anethum graveolens L.) on Aspergillus flavus

J Tian, X Ban, H Zeng, J He, Y Chen, Y Wang - PloS one, 2012 - journals.plos.org
The essential oil extracted from the seeds of dill (Anethum graveolens L.) was demonstrated
in this study as a potential source of an eco-friendly antifungal agent. To elucidate the …

[PDF][PDF] Reactive oxygen species in tumor progression

P Storz - Front biosci, 2005 - researchgate.net
Introduction 3. Reactive oxygen species in tumor growth and cellular survival 4. Reactive
oxygen species in cell motility and metastasis formation 5. Generation of reactive oxygen …

Autophagy inhibition enhances therapy-induced apoptosis in a Myc-induced model of lymphoma

RK Amaravadi, D Yu, JJ Lum, T Bui… - The Journal of clinical …, 2007 - jci.org
Autophagy is a lysosome-dependent degradative pathway frequently activated in tumor cells
treated with chemotherapy or radiation. Whether autophagy observed in treated cancer cells …

Oxidative stress in apoptosis and cancer: an update

JM Matés, JA Segura, FJ Alonso, J Márquez - Archives of toxicology, 2012 - Springer
The oxygen paradox tells us that oxygen is both necessary for aerobic life and toxic to all life
forms. Reactive oxygen species (ROS) touch every biological and medical discipline …

JNK signaling pathway is a key modulator in cell death mediated by reactive oxygen and nitrogen species

HM Shen, Z Liu - Free Radical Biology and Medicine, 2006 - Elsevier
c-Jun N-terminal kinase (JNK), or stress-activated protein kinase, is an important member of
the mitogen-activated protein kinase superfamily, the members of which are readily …

Reactive oxygen species in oncogenic transformation

L Behrend, G Henderson… - Biochemical society …, 2003 - portlandpress.com
Ever since ROS (reactive oxygen species) were shown to meet the criteria of true signalling
molecules, such as regulated production and a specific biological function, many efforts …