TFEB at a glance
The transcription factor EB (TFEB) plays a pivotal role in the regulation of basic cellular
processes, such as lysosomal biogenesis and autophagy. The subcellular localization and …
processes, such as lysosomal biogenesis and autophagy. The subcellular localization and …
The role of molecular testing in the differential diagnosis of salivary gland carcinomas
A Skálová, G Stenman, RHW Simpson… - The American journal …, 2018 - journals.lww.com
Salivary gland neoplasms are a morphologically heterogenous group of lesions that are
often diagnostically challenging. In recent years, considerable progress in salivary gland …
often diagnostically challenging. In recent years, considerable progress in salivary gland …
The kinase LKB1 mediates glucose homeostasis in liver and therapeutic effects of metformin
The Peutz-Jegher syndrome tumor-suppressor gene encodes a protein-threonine kinase,
LKB1, which phosphorylates and activates AMPK [adenosine monophosphate (AMP) …
LKB1, which phosphorylates and activates AMPK [adenosine monophosphate (AMP) …
[KNIHA][B] Pathology and genetics of tumours of soft tissue and bone
CDM Fletcher, KK Unni, F Mertens - 2002 - books.google.com
This WHO classification covers tumors of soft tissue and bone including inherited tumor
syndromes. Each entity is extensively discussed with information on clinicopathological …
syndromes. Each entity is extensively discussed with information on clinicopathological …
The Ewing family of tumors--a subgroup of small-round-cell tumors defined by specific chimeric transcripts
Background Precise diagnosis of small-round-cell tumors is often a challenge to the
pathologist and the clinical oncologist. In Ewing's sarcomas and related peripheral primitive …
pathologist and the clinical oncologist. In Ewing's sarcomas and related peripheral primitive …
Comparative study of the National Cancer Institute and French Federation of Cancer Centers Sarcoma Group grading systems in a population of 410 adult patients …
L Guillou, JM Coindre, F Bonichon… - Journal of clinical …, 1997 - ascopubs.org
PURPOSE Several histologic grading systems have been validated in soft tissue sarcomas
(STS), but no system is currently accepted worldwide. The National Cancer Institute (NCI) …
(STS), but no system is currently accepted worldwide. The National Cancer Institute (NCI) …
Chromosomal translocations in human cancer
TH Rabbitts - Nature, 1994 - nature.com
Chromosomal abnormalities in tumours were recognized at the end of the last century but
their significance has only recently become clear. Distinct translocations in leukaemias and …
their significance has only recently become clear. Distinct translocations in leukaemias and …
A second Ewing's sarcoma translocation, t (21; 22), fuses the EWS gene to another ETS–family transcription factor, ERG
Abstract The t (11; 22)(q24; q12), present in 85% of Ewing's sarcoma and related tumours,
fuses the EWS gene from chromosome 22q12 and the ETS family member, FLI–1. This …
fuses the EWS gene from chromosome 22q12 and the ETS family member, FLI–1. This …
Meta-analysis of three genome-wide association studies identifies susceptibility loci for colorectal cancer at 1q41, 3q26. 2, 12q13. 13 and 20q13. 33
RS Houlston, J Cheadle, SE Dobbins, A Tenesa… - Nature …, 2010 - nature.com
Genome-wide association studies (GWAS) have identified ten loci harboring common
variants that influence risk of develo** colorectal cancer (CRC). To enhance the power to …
variants that influence risk of develo** colorectal cancer (CRC). To enhance the power to …
The Ewing family of tumors: Ewing's sarcoma and primitive neuroectodermal tumors
HE Grier - Pediatric Clinics of North America, 1997 - Elsevier
The Ewing family of tumors (Ewing's sarcoma and primitive neuroectodermal tumor [PNET])
is the second most common malignant bone tumor (after osteogenic sarcoma) in children …
is the second most common malignant bone tumor (after osteogenic sarcoma) in children …