The brain is the central organ of stress and adaptation to stress because it perceives and
determines what is threatening, as well as the behavioral and physiological responses to the …

Energy is required to sustain life and enable stress adaptation. At the cellular level, energy is
largely derived from mitochondria–unique multifunctional organelles with their own genome …

INTRODUCTION Depression is an episodic form of mental illness, yet the circuit-level
mechanisms driving the induction, remission, and recurrence of depressive episodes over …

The analysis of hair cortisol concentrations (HCC) is a relatively new strategy to measure
long-term cumulative cortisol levels, which is increasingly used in …

Psychological stress is common in many physical illnesses and is increasingly recognized
as a risk factor for disease onset and progression. An emerging body of literature suggests …

The link between chronic psychosocial and metabolic stress and the pathogenesis of
disease has been extensively documented. Nevertheless, the cellular mechanisms by which …

The adverse metabolic effects of prescribed and endogenous glucocorticoid (GC) excess,
Cushing syndrome, create a significant health burden. We found that tissue regeneration of …

Recent studies have suggested that physiological and behavioral traits may be
transgenerationally inherited through the paternal lineage, possibly via non-genomic signals …

The prevalence of overweight and obesity has markedly increased during the past few
decades. Stress has been suggested as one environmental factor that may contribute to the …

Context: Although exposure to supraphysiological levels of glucocorticoids is known to
contribute to the development of the metabolic syndrome (MetS), the importance of …