Background Variant interpretation is essential for identifying patients' disease-causing
genetic variants amongst the millions detected in their genomes. Hundreds of Variant Impact …

The extent of parallel genomic responses to similar selective pressures depends on a
complex array of environmental, demographic, and evolutionary forces. Laboratory …

Characterising patterns of genetic diversity including evidence of local adaptation is relevant
for predicting and managing species recovering from overexploitation in the face of climate …

Background Rapid morphological change is emerging as a consequence of climate change
in many systems. It is intuitive to hypothesize that temporal morphological trends are driven …

Background Flight can drastically enhance dispersal capacity and is a key trait defining the
potential of exotic insect species to spread and invade new habitats. The phytophagous …

Background: Variant interpretation is essential for identifying patients' disease-causing
genetic variants amongst the millions detected in their genomes. Hundreds of Variant Impact …

A group of 54 exceptional responders (ER's) to cancer treatment across a variety of cancers
and treatments were compared to typical cancer patients using previously defined polygenic …

Linkage disequilibrium (LD) analysis is fundamental to the investigation of the genetic
architecture of complex traits (eg human disease, animal and plant breeding) and …

Background: Although a growing body of research suggests that alterations in the
composition of the immune system play a critical role in the development of colorectal …

Single nucleotide polymorphisms (SNPs) are the most common form of genetic sequence
variations. SNPs involve substitution of one nucleotide for another in the DNA sequence …