Cerebral microbleeds (CMBs), also referred to as microhemorrhages, appear on magnetic
resonance (MR) images as hypointense foci notably at T2*-weighted or susceptibility …

Importance After more than a decade of research and development of clinical trials testing
anti–β-amyloid monoclonal antibodies (mAbs), extensive experience has been gained …

Background Cerebral amyloid angiopathy (CAA) is an age-related small vessel disease,
characterised pathologically by progressive deposition of amyloid β in the cerebrovascular …

Implementation of amyloid biomarkers in clinical practice would be accelerated if such
biomarkers could be measured in blood. We analyzed plasma levels of Aβ42 and Aβ40 in a …

Cerebral microbleeds (CMBs) are small haemorrhages nearby blood vessels. They have
been recognized as important diagnostic biomarkers for many cerebrovascular diseases …

Cerebral small vessel disease (SVD) is a common accompaniment of ageing. Features seen
on neuroimaging include recent small subcortical infarcts, lacunes, white matter …

Ischemic stroke is a leading cause of global mortality and long-term disability. However,
there is a paucity of whole-genome sequencing studies on ischemic stroke, resulting in …

Background Cerebral microbleeds are a potential neuroimaging biomarker of cerebral small
vessel diseases that are prone to intracranial bleeding. We aimed to determine whether …

Background White matter hyperintensities (WMH), lacunes and microbleeds are regarded as
typical MRI expressions of cerebral small vessel disease (SVD) and they are highly …

White matter disruption is an important determinant of cognitive impairment after brain injury,
but conventional neuroimaging underestimates its extent. In contrast, diffusion tensor …