The oxytocin receptor: from intracellular signaling to behavior

B Jurek, ID Neumann - Physiological reviews, 2018‏ - journals.physiology.org
The many facets of the oxytocin (OXT) system of the brain and periphery elicited nearly
25,000 publications since 1930 (see, as listed in PubMed), which revealed central roles for …

How do antidepressants work? New perspectives for refining future treatment approaches

CJ Harmer, RS Duman, PJ Cowen - The Lancet Psychiatry, 2017‏ - thelancet.com
Most currently available antidepressants target monoamine neurotransmitter function.
However, a purely neurotransmitter-based explanation for antidepressant drug action is …

Probiotic Bifidobacterium longum NCC3001 reduces depression scores and alters brain activity: a pilot study in patients with irritable bowel syndrome

MI Pinto-Sanchez, GB Hall, K Ghajar, A Nardelli… - Gastroenterology, 2017‏ - Elsevier
Background & Aims Probiotics can reduce symptoms of irritable bowel syndrome (IBS), but
little is known about their effects on psychiatric comorbidities. We performed a prospective …

The role of the locus coeruleus in the generation of pathological anxiety

LS Morris, JG McCall, DS Charney… - Brain and …, 2020‏ - journals.sagepub.com
This review aims to synthesise a large pre-clinical and clinical literature related to a
hypothesised role of the locus coeruleus norepinephrine system in responses to acute and …

The nature, diagnosis, and treatment of neuroticism: Back to the future

DH Barlow, S Sauer-Zavala, JR Carl… - Clinical …, 2014‏ - journals.sagepub.com
We highlight the role of neuroticism in the development and course of emotional disorders
and make a case for shifting the focus of intervention to this higher-order dimension of …

The neurobiology of depression and antidepressant action

P Willner, J Scheel-Krüger, C Belzung - Neuroscience & biobehavioral …, 2013‏ - Elsevier
We present a comprehensive overview of the neurobiology of unipolar major depression
and antidepressant drug action, integrating data from affective neuroscience, neuro-and …

The neurocircuitry of fear, stress, and anxiety disorders

LM Shin, I Liberzon - Neuropsychopharmacology, 2010‏ - nature.com
Anxiety disorders are a significant problem in the community, and recent neuroimaging
research has focused on determining the brain circuits that underlie them. Research on the …

Neural correlates of dysfunctional emotion regulation in major depressive disorder. A systematic review of neuroimaging studies

MM Rive, G Van Rooijen, DJ Veltman… - Neuroscience & …, 2013‏ - Elsevier
Abnormal emotion processing is a core feature of major depressive disorder (MDD). Since
the emergence of functional neuroimaging techniques, many studies have been conducted …

Meta-analysis of emotion recognition deficits in major depressive disorder

MN Dalili, IS Penton-Voak, CJ Harmer… - Psychological …, 2015‏ - cambridge.org
Background. Many studies have explored associations between depression and facial
emotion recognition (ER). However, these studies have used various paradigms and …

Personality in a hierarchical model of psychopathology

TA Widiger, M Sellbom… - Clinical …, 2019‏ - journals.sagepub.com
The categorical model of classification in the fifth edition of the Diagnostic and Statistical
Manual of Mental Disorders is sorely problematic. A proposed solution is emerging in the …