The polypharmacological effects of cannabidiol

J Castillo-Arellano, A Canseco-Alba, SJ Cutler, F León - Molecules, 2023 - mdpi.com
Cannabidiol (CBD) is a major phytocannabinoid present in Cannabis sativa (Linneo, 1753).
This naturally occurring secondary metabolite does not induce intoxication or exhibit the …

Evaluation of hemp (Cannabis sativa L.) as an industrial crop: a review

M Rehman, S Fahad, G Du, X Cheng, Y Yang… - … Science and Pollution …, 2021 - Springer
Rising human population has increased the utilization of available resources for food,
clothes, medicine, and living space, thus menacing natural environment and mounting the …

Cannabidiol: pharmacology and therapeutic targets

SC Britch, S Babalonis, SL Walsh - Psychopharmacology, 2021 - Springer
Rationale Cannabidiol (CBD) products lacking regulatory approval are being used to self-
treat a myriad of conditions and for their unsubstantiated health benefits. The scientific …

Cannabidiol in anxiety and sleep: a large case series

S Shannon, N Lewis, H Lee… - The Permanente …, 2019 - pmc.ncbi.nlm.nih.gov
Context Cannabidiol (CBD) is one of many cannabinoid compounds found in cannabis. It
does not appear to alter consciousness or trigger a “high.” A recent surge in scientific …

[HTML][HTML] Cannabidiol: a potential new alternative for the treatment of anxiety, depression, and psychotic disorders

MS García-Gutiérrez, F Navarrete, A Gasparyan… - Biomolecules, 2020 - mdpi.com
The potential therapeutic use of some Cannabis sativa plant compounds has been attracting
great interest, especially for managing neuropsychiatric disorders due to the relative lack of …

Cannabidiol modulates serotonergic transmission and reverses both allodynia and anxiety-like behavior in a model of neuropathic pain

D De Gregorio, RJ McLaughlin, L Posa… - Pain, 2019 - journals.lww.com
Clinical studies indicate that cannabidiol (CBD), the primary nonaddictive component of
cannabis that interacts with the serotonin (5-HT) 1A receptor, may possess analgesic and …

Cannabidiol: State of the art and new challenges for therapeutic applications

S Pisanti, AM Malfitano, E Ciaglia, A Lamberti… - Pharmacology & …, 2017 - Elsevier
Over the past years, several lines of evidence support a therapeutic potential of Cannabis
derivatives and in particular phytocannabinoids. Δ 9-THC and cannabidiol (CBD) are the …

Translational investigation of the therapeutic potential of cannabidiol (CBD): toward a new age

JA Crippa, FS Guimarães, AC Campos… - Frontiers in …, 2018 - frontiersin.org
Background: Among the many cannabinoids in the cannabis plant, cannabidiol (CBD) is a
compound that does not produce the typical subjective effects of marijuana. Objectives: The …

The “entourage effect”: terpenes coupled with cannabinoids for the treatment of mood disorders and anxiety disorders

SG Ferber, D Namdar, D Hen-Shoval… - Current …, 2020 - ingentaconnect.com
Mood disorders are the most prevalent mental conditions encountered in psychiatric
practice. Numerous patients suffering from mood disorders present with treatment-resistant …

Medicinal properties of cannabinoids, terpenes, and flavonoids in cannabis, and benefits in migraine, headache, and pain: an update on current evidence and …

EP Baron - Headache: The Journal of Head and Face Pain, 2018 - Wiley Online Library
Background Comprehensive literature reviews of historical perspectives and evidence
supporting cannabis/cannabinoids in the treatment of pain, including migraine and …