Aggregation-induced emission (AIE), life and health

H Wang, Q Li, P Alam, H Bai, V Bhalla, MR Bryce… - ACS …, 2023‏ - ACS Publications
Light has profoundly impacted modern medicine and healthcare, with numerous
luminescent agents and imaging techniques currently being used to assess health and treat …

Shining new light on biological systems: luminescent transition metal complexes for bioimaging and biosensing applications

LCC Lee, KKW Lo - Chemical Reviews, 2024‏ - ACS Publications
Luminescence imaging is a powerful and versatile technique for investigating cell
physiology and pathology in living systems, making significant contributions to life science …

Recent advances in contrast-enhanced photoacoustic imaging: overcoming the physical and practical challenges

W Choi, B Park, S Choi, D Oh, J Kim, C Kim - Chemical Reviews, 2023‏ - ACS Publications
For decades now, photoacoustic imaging (PAI) has been investigated to realize its potential
as a niche biomedical imaging modality. Despite its highly desirable optical contrast and …

Near-infrared metal agents assisting precision medicine: from strategic design to bioimaging and therapeutic applications

C Li, Y Pang, Y Xu, M Lu, L Tu, Q Li… - Chemical Society …, 2023‏ - pubs.rsc.org
Metal agents have made incredible strides in preclinical research and clinical applications in
recent years, but their short emission/absorption wavelengths continue to be a barrier to …

Activatable fluorescent probes for in situ imaging of enzymes

X Wu, R Wang, N Kwon, H Ma, J Yoon - Chemical Society Reviews, 2022‏ - pubs.rsc.org
As the main biomarkers of most diseases, enzymes play fundamental but extremely critical
roles in biosystems. High-resolution studies of enzymes using activatable in situ …

Rational design of NIR-II AIEgens with ultrahigh quantum yields for photo-and chemiluminescence imaging

H Shen, F Sun, X Zhu, J Zhang, X Ou… - Journal of the …, 2022‏ - ACS Publications
Fluorescence imaging in the second near-infrared window (NIR-II, 1000–1700 nm) using
small-molecule dyes has high potential for clinical use. However, many NIR-II dyes suffer …

Second near-infrared photothermal materials for combinational nanotheranostics

C Xu, K Pu - Chemical Society Reviews, 2021‏ - pubs.rsc.org
Second near-infrared photothermal therapy (NIR-II PTT, 1000–1500 nm) has recently
emerged as a new phototherapeutic modality with the advantages of deeper penetration …

Molecular probes for autofluorescence-free optical imaging

Y Jiang, K Pu - Chemical reviews, 2021‏ - ACS Publications
Optical imaging is an indispensable tool in clinical diagnostics and fundamental biomedical
research. Autofluorescence-free optical imaging, which eliminates real-time optical …

Advanced fluorescence imaging technology in the near-infrared-II window for biomedical applications

C Li, G Chen, Y Zhang, F Wu… - Journal of the American …, 2020‏ - ACS Publications
Fluorescence imaging has become a fundamental tool for biomedical applications;
nevertheless, its intravital imaging capacity in the conventional wavelength range (400–950 …

Chemical design of activatable photoacoustic probes for precise biomedical applications

Y Liu, L Teng, B Yin, H Meng, X Yin, S Huan… - Chemical …, 2022‏ - ACS Publications
Photoacoustic (PA) imaging technology, a three-dimensional hybrid imaging modality that
integrates the advantage of optical and acoustic imaging, has great application prospects in …