Pulmonary fibrosis as a result of acute lung inflammation: molecular mechanisms, relevant in vivo models, prognostic and therapeutic approaches

IA Savin, MA Zenkova, AV Sen'kova - International journal of molecular …, 2022 - mdpi.com
Pulmonary fibrosis is a chronic progressive lung disease that steadily leads to lung
architecture disruption and respiratory failure. The development of pulmonary fibrosis is …

Renal fibrosis in lupus nephritis

S Sciascia, M Cozzi, A Barinotti, M Radin… - International Journal of …, 2022 - mdpi.com
Fibrosis can be defined as a pathological process in which deposition of connective tissue
replaces normal parenchyma. The kidney, like any organ or tissue, can be impacted by this …

Dapagliflozin alleviates renal inflammation and protects against diabetic kidney diseases, both dependent and independent of blood glucose levels

A Cai, J Shen, X Yang, X Shao, L Gu, S Mou… - Frontiers in …, 2023 - frontiersin.org
Introduction Diabetic kidney disease (DKD) has become the leading cause of end-stage
renal disease worldwide. Therefore, efforts to understand DKD pathophysiology and prevent …

[HTML][HTML] Exploring the single-cell immune landscape of kidney allograft inflammation using imaging mass cytometry

MP Alexander, M Zaidi, N Larson, A Mullan… - American Journal of …, 2024 - Elsevier
Kidney allograft inflammation, mostly attributed to rejection and infection, is an important
cause of graft injury and loss. Standard histopathological assessment of allograft …

Targeting immune checkpoints in anti-neutrophil cytoplasmic antibodies associated vasculitis: the potential therapeutic targets in the future

M Pan, H Zhao, R **, PSC Leung, Z Shuai - Frontiers in Immunology, 2023 - frontiersin.org
Anti-neutrophil cytoplasmic autoantibodies (ANCA) associated vasculitis (AAV) is a
necrotizing vasculitis mainly involving small blood vessels. It is demonstrated that T cells are …

Dysregulated phosphate metabolism in autism spectrum disorder: associations and insights for future research

RB Brown - Expert Reviews in Molecular Medicine, 2023 - cambridge.org
Studies of autism spectrum disorder (ASD) related to exposure to toxic levels of dietary
phosphate are lacking. Phosphate toxicity from dysregulated phosphate metabolism can …

Maresin conjugates in tissue regeneration-1 suppresses ferroptosis in septic acute kidney injury

J **ao, Q Yang, Y Zhang, H Xu, Y Ye, L Li, Y Yang… - Cell & Bioscience, 2021 - Springer
Background Ferroptosis is unique among different types of regulated cell death and closely
related to organ injury. Whether ferroptosis occurs in sepsis-associated acute kidney injury …

Kidney immunology from pathophysiology to clinical translation

C Kurts, S von Vietinghoff, CF Krebs… - Nature Reviews …, 2025 - nature.com
Kidney diseases are widespread and represent a considerable medical, social and
economic burden. However, there has been marked progress in understanding the …

Fingolimod (FTY720) Hinders Interferon-γ-Mediated Fibrotic Scar Formation and Facilitates Neurological Recovery After Spinal Cord Injury

Y Li, Y Chen, X Hu, F Ouyang, J Li, J Huang… - Journal of …, 2023 - liebertpub.com
Following spinal cord injury (SCI), fibrotic scar inhibits axon regeneration and impairs
neurological function recovery. It has been reported that T cell–derived interferon (IFN)-γ …

MicroRNA-29b Plays a Vital Role in Podocyte Injury and Glomerular Diseases through Inducing Mitochondrial Dysfunction

J Liu, Y **ong, H Mo, H Niu, J Miao… - International …, 2024 - pmc.ncbi.nlm.nih.gov
Diabetic kidney disease (DKD) is becoming the most leading cause of end-stage renal
disease (ESRD). Podocyte injury plays a critical role in DKD progression. Notably …