Pulmonary fibrosis as a result of acute lung inflammation: molecular mechanisms, relevant in vivo models, prognostic and therapeutic approaches
IA Savin, MA Zenkova, AV Sen'kova - International journal of molecular …, 2022 - mdpi.com
Pulmonary fibrosis is a chronic progressive lung disease that steadily leads to lung
architecture disruption and respiratory failure. The development of pulmonary fibrosis is …
architecture disruption and respiratory failure. The development of pulmonary fibrosis is …
Renal fibrosis in lupus nephritis
S Sciascia, M Cozzi, A Barinotti, M Radin… - International Journal of …, 2022 - mdpi.com
Fibrosis can be defined as a pathological process in which deposition of connective tissue
replaces normal parenchyma. The kidney, like any organ or tissue, can be impacted by this …
replaces normal parenchyma. The kidney, like any organ or tissue, can be impacted by this …
Dapagliflozin alleviates renal inflammation and protects against diabetic kidney diseases, both dependent and independent of blood glucose levels
A Cai, J Shen, X Yang, X Shao, L Gu, S Mou… - Frontiers in …, 2023 - frontiersin.org
Introduction Diabetic kidney disease (DKD) has become the leading cause of end-stage
renal disease worldwide. Therefore, efforts to understand DKD pathophysiology and prevent …
renal disease worldwide. Therefore, efforts to understand DKD pathophysiology and prevent …
[HTML][HTML] Exploring the single-cell immune landscape of kidney allograft inflammation using imaging mass cytometry
Kidney allograft inflammation, mostly attributed to rejection and infection, is an important
cause of graft injury and loss. Standard histopathological assessment of allograft …
cause of graft injury and loss. Standard histopathological assessment of allograft …
Targeting immune checkpoints in anti-neutrophil cytoplasmic antibodies associated vasculitis: the potential therapeutic targets in the future
M Pan, H Zhao, R **, PSC Leung, Z Shuai - Frontiers in Immunology, 2023 - frontiersin.org
Anti-neutrophil cytoplasmic autoantibodies (ANCA) associated vasculitis (AAV) is a
necrotizing vasculitis mainly involving small blood vessels. It is demonstrated that T cells are …
necrotizing vasculitis mainly involving small blood vessels. It is demonstrated that T cells are …
Dysregulated phosphate metabolism in autism spectrum disorder: associations and insights for future research
RB Brown - Expert Reviews in Molecular Medicine, 2023 - cambridge.org
Studies of autism spectrum disorder (ASD) related to exposure to toxic levels of dietary
phosphate are lacking. Phosphate toxicity from dysregulated phosphate metabolism can …
phosphate are lacking. Phosphate toxicity from dysregulated phosphate metabolism can …
Maresin conjugates in tissue regeneration-1 suppresses ferroptosis in septic acute kidney injury
J **ao, Q Yang, Y Zhang, H Xu, Y Ye, L Li, Y Yang… - Cell & Bioscience, 2021 - Springer
Background Ferroptosis is unique among different types of regulated cell death and closely
related to organ injury. Whether ferroptosis occurs in sepsis-associated acute kidney injury …
related to organ injury. Whether ferroptosis occurs in sepsis-associated acute kidney injury …
Kidney immunology from pathophysiology to clinical translation
C Kurts, S von Vietinghoff, CF Krebs… - Nature Reviews …, 2025 - nature.com
Kidney diseases are widespread and represent a considerable medical, social and
economic burden. However, there has been marked progress in understanding the …
economic burden. However, there has been marked progress in understanding the …
Fingolimod (FTY720) Hinders Interferon-γ-Mediated Fibrotic Scar Formation and Facilitates Neurological Recovery After Spinal Cord Injury
Y Li, Y Chen, X Hu, F Ouyang, J Li, J Huang… - Journal of …, 2023 - liebertpub.com
Following spinal cord injury (SCI), fibrotic scar inhibits axon regeneration and impairs
neurological function recovery. It has been reported that T cell–derived interferon (IFN)-γ …
neurological function recovery. It has been reported that T cell–derived interferon (IFN)-γ …
MicroRNA-29b Plays a Vital Role in Podocyte Injury and Glomerular Diseases through Inducing Mitochondrial Dysfunction
J Liu, Y **ong, H Mo, H Niu, J Miao… - International …, 2024 - pmc.ncbi.nlm.nih.gov
Diabetic kidney disease (DKD) is becoming the most leading cause of end-stage renal
disease (ESRD). Podocyte injury plays a critical role in DKD progression. Notably …
disease (ESRD). Podocyte injury plays a critical role in DKD progression. Notably …