The role of molecular testing in the differential diagnosis of salivary gland carcinomas

A Skálová, G Stenman, RHW Simpson… - The American journal …, 2018 - journals.lww.com
Salivary gland neoplasms are a morphologically heterogenous group of lesions that are
often diagnostically challenging. In recent years, considerable progress in salivary gland …

Salivary gland carcinoma: novel targets to overcome treatment resistance in advanced disease

L Di Villeneuve, IL Souza, FDS Tolentino… - Frontiers in …, 2020 - frontiersin.org
Salivary gland carcinomas (SGC) account for less than 5% of head and neck malignant
neoplasms, further subcategorized in over 20 histological subtypes. For the most part …

[HTML][HTML] Targeted therapy for advanced salivary gland carcinoma based on molecular profiling: results from MyPathway, a phase IIa multiple basket study

R Kurzrock, DW Bowles, H Kang, F Meric-Bernstam… - Annals of …, 2020 - Elsevier
Background Systemic therapy options for salivary cancers are limited. MyPathway
(NCT02091141), a phase IIa study, evaluates targeted therapies in non-indicated tumor …

Molecular pathology of salivary gland neoplasms: diagnostic, prognostic, and predictive perspective

MH Toper, S Sarioglu - Advances in anatomic pathology, 2021 - journals.lww.com
Salivary gland neoplasms are an uncommon and widely heterogeneous group of tumors. In
recent years, there has been considerable progress in efforts to reveal the molecular …

The CRTC1-MAML2 fusion is the major oncogenic driver in mucoepidermoid carcinoma

Z Chen, W Ni, JL Li, S Lin, X Zhou, Y Sun, JW Li… - JCI …, 2021 - pmc.ncbi.nlm.nih.gov
No effective systemic treatment is available for patients with unresectable, recurrent, or
metastatic mucoepidermoid carcinoma (MEC), the most common salivary gland malignancy …

[HTML][HTML] Comprehensive genomic profiles of metastatic and relapsed salivary gland carcinomas are associated with tumor type and reveal new routes to targeted …

JS Ross, LM Gay, K Wang, JA Vergilio, J Suh… - Annals of …, 2017 - Elsevier
Background Relapsed/metastatic salivary gland carcinomas (SGCs) have a wide diversity of
histologic subtypes associated with variable clinical aggressiveness and response to local …

Pulmonary salivary gland tumor, mucoepidermoid carcinoma: a literature review

S Hu, J Gong, X Zhu, H Lu - Journal of Oncology, 2022 - Wiley Online Library
Pulmonary mucoepidermoid carcinoma (PMEC) is the most common malignant salivary
gland tumor in the lungs and accounts for 0.1‐0.2% of all lung malignancies in adults. It has …

Mucoepidermoid carcinoma of the salivary gland: demographics and comparative analysis in US children and adults with future perspective of management

A Ullah, J Khan, A Waheed, NR Karki, M Goodbee… - Cancers, 2022 - mdpi.com
Simple Summary Salivary gland tumors are rare among both pediatric and adult
populations. Mucoepidermoid carcinoma (MEC) is a common type of malignant salivary …

Comprehensive genomic profiling of salivary gland carcinoma: Analysis of the Center for Cancer Genomics and Advanced Therapeutics database in Japan

S Iwaki, D Kawakita, T Nagao, Y Tada… - … Journal of Cancer, 2024 - Wiley Online Library
Comprehensive information on genetic alterations in salivary gland cancer (SGC) is limited.
This study aimed to elucidate the genetic and clinical characteristics of patients with SGC …

Recurrent IDH2 mutations in salivary gland striated duct adenoma define an expanded histologic spectrum distinct from canalicular adenoma

LM Rooper, A Agaimy, A Assaad, M Bal… - The American Journal …, 2023 - journals.lww.com
Striated duct adenoma (SDA) is a rare salivary gland neoplasm defined by histologic
similarity to normal striated ducts. However, doubt persists about whether SDA represents a …