The pandemic of novel coronavirus disease 2019 (COVID-19) has rampaged the world, with
more than 58.4 million confirmed cases and over 1.38 million deaths across the world by 23 …

Background Following the outbreak of the COVID-19 pandemic, there was a surge of
research activity to find methods/drugs to treat it. There has been drug-repurposing research …

For the last two years, the COVID-19 pandemic has continued to bring consternation on
most of the world. According to recent WHO estimates, there have been more than 5.6 …

The global outbreak of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)
necessitates the rapid development of new therapies against coronavirus disease 2019 …

The Coronavirus disease 2019 (COVID-19) outbreak was declared by the World Health
Organization (WHO) in March 2020 to be a pandemic and many drugs used at the beginning …

Purpose The development of effective treatments for coronavirus infectious disease 19
(COVID-19) caused by SARS-Coronavirus-2 was hindered by the little data available about …

Using as a template the crystal structure of the SARS-CoV-2 main protease, we developed a
pharmacophore model of functional centers of the protease inhibitor-binding pocket. With …

This study demonstrates the inhibitory effect of 42 pyrimidonic pharmaceuticals (PPs) on the
3-chymotrypsin-like protease of SARS-CoV-2 (3CLpro) through molecular docking …

Objective: The receptor-binding domain (RBD) of the S1 domain of the SARS-CoV-2 Spike
protein performs a key role in the interaction with Angiotensin-converting enzyme 2 (ACE2) …

Background: Following the outbreak of the COVID-19 pandemic, there was a surge of
research activity to find methods/drugs to treat it. There has been drug-repurposing research …