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[HTML][HTML] Tobacco smoke induces and alters immune responses in the lung triggering inflammation, allergy, asthma and other lung diseases: a mechanistic review
Many studies have been undertaken to reveal how tobacco smoke skews immune
responses contributing to the development of chronic obstructive pulmonary disease …
responses contributing to the development of chronic obstructive pulmonary disease …
Nicotine-induced epithelial-mesenchymal transition via Wnt/β-catenin signaling in human airway epithelial cells
W Zou, Y Zou, Z Zhao, B Li… - American Journal of …, 2013 - journals.physiology.org
Epithelial-mesenchymal transition (EMT) has been proposed to be a mechanism in airway
remodeling, which is a characteristic of chronic obstructive pulmonary disease (COPD) …
remodeling, which is a characteristic of chronic obstructive pulmonary disease (COPD) …
A flavanone from Baccharis retusa (Asteraceae) prevents elastase-induced emphysema in mice by regulating NF-κB, oxidative stress and metalloproteinases
Background Pulmonary emphysema is characterized by irreversible airflow obstruction,
inflammation, oxidative stress imbalance and lung remodeling, resulting in reduced lung …
inflammation, oxidative stress imbalance and lung remodeling, resulting in reduced lung …
Cigarette smoke extract induces a phenotypic shift in epithelial cells; involvement of HIF1α in mesenchymal transition
In COPD, matrix remodeling contributes to airflow limitation. Recent evidence suggests that
next to fibroblasts, the process of epithelial-mesenchymal transition can contribute to matrix …
next to fibroblasts, the process of epithelial-mesenchymal transition can contribute to matrix …
Smoking accelerates renal cystic disease and worsens cardiac phenotype in Pkd1-deficient mice
Smoking has been associated with renal disease progression in ADPKD but the underlying
deleterious mechanisms and whether it specifically worsens the cardiac phenotype remain …
deleterious mechanisms and whether it specifically worsens the cardiac phenotype remain …
Rice Bran Oil Improves Emphysema in cigarette smoke Extract-Induced mice through anti-inflammatory and Antioxidative effects
A Kettawan, S Ruangklai, T Rungruang, J Thongam… - Nutrients, 2024 - mdpi.com
Lung inflammation and alveolar enlargement are the major pathological conditions of
chronic obstructive pulmonary disease (COPD) patients. Rice bran oil (RBO), a natural anti …
chronic obstructive pulmonary disease (COPD) patients. Rice bran oil (RBO), a natural anti …
Human tubal-derived mesenchymal stromal cells associated with low level laser therapy significantly reduces cigarette smoke–induced COPD in C57BL/6 mice
Cigarette smoke-induced chronic obstructive pulmonary disease is a very debilitating
disease, with a very high prevalence worldwide, which results in a expressive economic and …
disease, with a very high prevalence worldwide, which results in a expressive economic and …
Microenvironmental stimuli induce different macrophage polarizations in experimental models of emphysema
JB Kohler, DAB Cervilha, A Riani Moreira… - Biology …, 2019 - journals.biologists.com
Macrophages play a pivotal role in the development of emphysema and depending on the
microenvironment stimuli can be polarized into M1-or M2-like macrophage phenotypes. We …
microenvironment stimuli can be polarized into M1-or M2-like macrophage phenotypes. We …
iNOS inhibition reduces lung mechanical alterations and remodeling induced by particulate matter in mice
Background. The epidemiologic association between pulmonary exposure to ambient
particulate matter (PM) and acute lung damage is well known. However, the mechanism …
particulate matter (PM) and acute lung damage is well known. However, the mechanism …
Combined Effects of in Utero and Adolescent Tobacco Smoke Exposure on Lung Function in C57Bl/6J Mice
Background: Fetal determinants of airway function, such as in utero exposure to maternal
cigarette smoke (CS), may create a predisposition to adult airflow obstruction and chronic …
cigarette smoke (CS), may create a predisposition to adult airflow obstruction and chronic …