In the present investigation, detailed two-phase flow modeling of airflow, transport and
deposition of micro-particles (1–10 µm) in a realistic tracheobronchial airway geometry …

An understanding of human inter-subject variability is crucial for the implementation of
personalized pulmonary drug delivery as well as exposure assessment of airborne …

Computational modeling together with experimental data are essential to assess the risk for
particulate matter mediated lung toxicity and to predict the efficacy, safety and fate of …

Determining the impact of inter-subject variability on airflow pattern and nanoparticle
deposition in the human respiratory system is necessary to generate population …

This study presents a series of numerical simulations for airflow field and particle dispersion
and deposition around a mannequin inside a ventilated room. A 3-D airway system of a …

Inhalation of aerosols such as pharmaceutical aerosols or virus aerosol uptake is of great
concern to the human population. To elucidate the underlying aerosol dynamics, the …

Dispositions of inhalable particles in the human respiratory tract trigger and exacerbate
airway inflammatory diseases. However, the particle deposition (PD) in airway of subjects …

The main goal of this study is the quantification of the particle transport and deposition within
the human airways during light, normal and exercise breathing conditions using the …

Present study describes a systematic process involved in the preparation of a suitable lung
airway model using MIMICS 20.0 software. The CAD model can be prepared using manual …

In this chapter, we review the current state of in silico tools for lung deposition applications
and discuss how knowledge gathered from recent studies can be purposefully leveraged to …