Carbohydrates are the most abundant organic compounds in nature, widely distributed in
animals, plants and microorganisms. In order to understanding their structure properties, the …

This review is the tenth update of the original article published in 1999 on the application of
matrix‐assisted laser desorption/ionization (MALDI) mass spectrometry to the analysis of …

N-linked glycosylation is one of the most important post-translational modifications of
proteins. Current knowledge of multicellular eukaryote N-glycan biosynthesis suggests high …

N-linked glycosylation is one of the most important protein post-translational modifications.
Despite the importance of N-glycans, the structural determination of N-glycan isomers …

Previous exploration of the conformational space of sodiated mono-saccharides using a
random search algorithm leads to∼ 103 structurally distinct conformers covering an energy …

Rational Electrospray ionization (ESI) and matrix‐assisted laser desorption ionization
(MALDI) are soft ionization techniques commonly used in mass spectrometry. Although in …

Glycans have diverse functions and play vital roles in many biological systems, such as
influenza, vaccines, and cancer biomarkers. However, full structural identification of glycans …

Sampling the conformational space of monosaccharides using the first-principles methods is
important and as a database of local minima provides a solid base for interpreting …

Structure determination is a longstanding bottleneck of carbohydrate research. Tandem
mass spectrometry (MS/MS) is one of the most widely used methods for carbohydrate …

In the last ten years, combinations of state-of-the-art gas-phase spectroscopies and quantum
chemistry calculations have suggested several intuitive trends in the structure of small …